Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS14098  |
| T6SS type | Type i2 |
| Strain | Enterobacter cloacae strain DSM 30054 |
| Replicon (RefSeq) | chromosome (NZ_CP056776) |
| Location | 4297267..4345922 |
| Function | - |
| Comment | Deletion of the tssB1 gene in those predatory strains that were genetically tractable, which abrogated their interbacterial killing capacity. The T6SS-2-impaired mutant (ΔtssB2) of Enterobacter strain did not contribute to the antibacterial killing activity under the tested conditions. |
| References | [1] Flaugnatti N, Isaac S, Lemos Rocha LF, Stutzmann S, Rendueles O, Stoudmann C, Vesel N, Garcia-Garcera M, Buffet A, Sana TG, Rocha EPC, Blokesch M. et al (2021) Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms.. Nat Commun. 12(1):5751. [PudMed:34599171] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssE | TssG | TssJ | TssK | TssL | TssM |
| Number | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| HWQ16_RS21020 | 4292596..4293510 | + | 915 | WP_044158335.1 | OmpG family monomeric porin | ||
| HWQ16_RS21025 | 4293545..4294555 | - | 1011 | WP_013096418.1 | LacI family transcriptional regulator | ||
| HWQ16_RS21030 | 4294707..4296104 | + | 1398 | WP_013096419.1 | YcjX family protein | ||
| HWQ16_RS21035 | 4296101..4297153 | + | 1053 | WP_013096420.1 | YcjF family protein | ||
| HWQ16_RS21040 (tyrR) | 4297267..4298808 | + | 1542 | WP_013096421.1 | transcriptional regulator TyrR | ||
| HWQ16_RS21045 | 4298845..4300053 | - | 1209 | WP_013096422.1 | aldose 1-epimerase family protein | ||
| HWQ16_RS21050 (tpx) | 4300373..4300879 | - | 507 | WP_013096423.1 | thiol peroxidase | ||
| HWQ16_RS21055 (ycjG) | 4300987..4301952 | + | 966 | WP_013096424.1 | L-Ala-D/L-Glu epimerase | ||
| HWQ16_RS21060 (mpaA) | 4301943..4302656 | - | 714 | WP_013096425.1 | murein tripeptide amidase MpaA | ||
| HWQ16_RS21065 | 4302839..4304455 | + | 1617 | WP_013096426.1 | peptide ABC transporter substrate-binding protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||