Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00932  |
| T6SS type | Type Unknown |
| Strain | Burkholderia pseudomallei Bp340 |
| Replicon (GenBank) | (-) |
| Location | - |
| Function | anti-eukaryotic |
| Comment | VgrG5 mediates membrane fusion during intercellular spread by Pseudomallei group Burkholderia species; VgrG5 C-terminal domain is required for T6SS-mediated cell death. |
| References | [1] Toesca IJ et al (2014) The Type VI Secretion System Spike Protein VgrG5 Mediates Membrane Fusion during Intercellular Spread by Pseudomallei Group Burkholderia Species. Infect Immun. 82(4):1436-44. [PudMed:24421040] |
Experimental investigation has been performed.