Detailed information NTG0998970

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ABD407_RS04935
• Genome accession: NZ_CP155736
• Coordinates: 970284..971120 (+)
• Length: 278 a.a.
• NCBI ID: WP_023611998.1
• Uniprot ID: A0A5S4TFX7
• Organism: Streptococcus pyogenes strain 1966/14
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 965284..976120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABD407_RS04905 (ABD407_04880)	-	965838..966206 (+)	369	WP_010922310.1	hypothetical protein	-
ABD407_RS04910 (ABD407_04885)	-	966256..967167 (-)	912	WP_023612012.1	diacylglycerol kinase family protein	-
ABD407_RS04915 (ABD407_04890)	-	967284..967934 (-)	651	WP_002984629.1	hemolysin III family protein	-
ABD407_RS04920 (ABD407_04895)	-	967931..968371 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ABD407_RS04925 (ABD407_04900)	ylqF	968590..969438 (+)	849	WP_023611994.1	ribosome biogenesis GTPase YlqF	-
ABD407_RS04930 (ABD407_04905)	-	969428..970219 (+)	792	WP_023612045.1	ribonuclease HII	-
ABD407_RS04935 (ABD407_04910)	dprA	970284..971120 (+)	837	WP_023611998.1	DNA-processing protein DprA	Machinery gene
ABD407_RS04940 (ABD407_04915)	topA	971228..973357 (+)	2130	WP_050336211.1	type I DNA topoisomerase	-
ABD407_RS04945 (ABD407_04920)	-	973432..974316 (-)	885	Protein_927	LysR family transcriptional regulator	-
ABD407_RS04950 (ABD407_04925)	-	974329..974895 (+)	567	Protein_928	PTS sugar transporter subunit IIC	-
ABD407_RS04955 (ABD407_04930)	-	974910..975902 (+)	993	WP_023612447.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30958.92 Da
• Isoelectric Point: 8.8230

>NTDB_id=998970 ABD407_RS04935 WP_023611998.1 970284..971120(+) (dprA) [Streptococcus pyogenes strain 1966/14]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGAACVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=998970 ABD407_RS04935 WP_023611998.1 970284..971120(+) (dprA) [Streptococcus pyogenes strain 1966/14]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAGCATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A5S4TFX7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367