Detailed information NTG0997430

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: ABC804_RS05110
• Genome accession: NZ_CP155536
• Coordinates: 936045..936893 (+)
• Length: 282 a.a.
• NCBI ID: WP_000705300.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain M264-3
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 931045..941893

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC804_RS05085 (ABC804_05085)	-	931770..932477 (+)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
ABC804_RS05090 (ABC804_05090)	-	932482..933504 (+)	1023	WP_000609890.1	ribitol-5-phosphate dehydrogenase	-
ABC804_RS05095 (ABC804_05095)	licA	933521..934390 (+)	870	WP_000411215.1	choline kinase LicA	-
ABC804_RS05100 (ABC804_05100)	-	934380..935258 (+)	879	WP_000837618.1	DMT family transporter	-
ABC804_RS05105 (ABC804_05105)	-	935270..935959 (+)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
ABC804_RS05110 (ABC804_05110)	dprA/cilB/dalA	936045..936893 (+)	849	WP_000705300.1	DNA-processing protein DprA	Machinery gene
ABC804_RS05115 (ABC804_05115)	-	937076..937198 (-)	123	WP_001814242.1	hypothetical protein	-
ABC804_RS05120 (ABC804_05120)	-	937775..938818 (+)	1044	WP_001812883.1	TIGR00341 family protein	-
ABC804_RS05125 (ABC804_05125)	topA	938985..941072 (+)	2088	WP_000179682.1	type I DNA topoisomerase	-
ABC804_RS05130 (ABC804_05130)	-	941293..941652 (+)	360	WP_001237219.1	YbaN family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31048.70 Da
• Isoelectric Point: 5.4047

>NTDB_id=997430 ABC804_RS05110 WP_000705300.1 936045..936893(+) (dprA/cilB/dalA) [Streptococcus pneumoniae strain M264-3]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDIFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=997430 ABC804_RS05110 WP_000705300.1 936045..936893(+) (dprA/cilB/dalA) [Streptococcus pneumoniae strain M264-3]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAACAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGCTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATATCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.291	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis SK321	97.163	100	0.972
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55.714	99.291	0.553
dprA	Staphylococcus aureus N315	37.102	100	0.372