Detailed information NTG0997321

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ABC811_RS05565
• Genome accession: NZ_CP155535
• Coordinates: 1080853..1083093 (-)
• Length: 746 a.a.
• NCBI ID: WP_000942422.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PJ755/1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1075853..1088093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC811_RS05530 (ABC811_05525)	-	1076754..1077134 (-)	381	WP_000157154.1	VOC family protein	-
ABC811_RS05535 (ABC811_05530)	rplT	1077192..1077551 (-)	360	WP_000124836.1	50S ribosomal protein L20	-
ABC811_RS05540 (ABC811_05535)	rpmI	1077603..1077803 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
ABC811_RS05545 (ABC811_05540)	infC	1077836..1078366 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
ABC811_RS05550 (ABC811_05545)	-	1078687..1079862 (-)	1176	WP_000655940.1	hypothetical protein	-
ABC811_RS05555 (ABC811_05550)	-	1079866..1080453 (-)	588	WP_000933542.1	ABC transporter ATP-binding protein	-
ABC811_RS05560 (ABC811_05555)	-	1080485..1080673 (-)	189	WP_010976492.1	hypothetical protein	-
ABC811_RS05565 (ABC811_05560)	comEC/celB	1080853..1083093 (-)	2241	WP_000942422.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ABC811_RS05570 (ABC811_05565)	comEA/celA/cilE	1083077..1083727 (-)	651	WP_000387352.1	helix-hairpin-helix domain-containing protein	Machinery gene
ABC811_RS05575 (ABC811_05570)	-	1083795..1084364 (-)	570	WP_000443745.1	GNAT family N-acetyltransferase	-
ABC811_RS05580 (ABC811_05575)	ald	1084541..1085652 (+)	1112	Protein_1103	alanine dehydrogenase	-
ABC811_RS05585 (ABC811_05580)	-	1085953..1086279 (-)	327	Protein_1104	TfoX/Sxy family protein	-
ABC811_RS05590 (ABC811_05585)	-	1086282..1086782 (-)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
ABC811_RS05595 (ABC811_05590)	-	1086962..1087930 (-)	969	WP_000658181.1	PhoH family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84696.39 Da
• Isoelectric Point: 9.4461

>NTDB_id=997321 ABC811_RS05565 WP_000942422.1 1080853..1083093(-) (comEC/celB) [Streptococcus pneumoniae strain PJ755/1]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCLFIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=997321 ABC811_RS05565 WP_000942422.1 1080853..1083093(-) (comEC/celB) [Streptococcus pneumoniae strain PJ755/1]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTATGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGTTTTGTTTTTCTGCTAGTCTGCCTCTTTATCCAATTTCCTTGGAAATCAGCAG
GTAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAACTTGGCAACAGAGTCAAGTGAGTCAAAAT
TTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTTAACGGTGACAGTCTGTCCTTTCGTGGTAA
GTCTGATGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACTGACC
TTCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGGCTAT
CTGAAGACTCAGGGAATTTACCAGACACTCAATATTAAAAGAATCCAGTCACTCCAAAAGGTTGGCAGTTGGGATATAGG
TGAAAACCTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGATGCACTTCCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTAGGACATCTGGACACCGATTTTGAGGAGATGAATGAGCTTTATTCCAGTTTAGGAATTATTCACCTT
TTTGCCTTGTCAGGTATGCAGGTAGGGTTTTTCATGGACGGATTTAAGAAACTACTTTTACGATTGGGCTTGACACAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGTGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAAGCTTGATACCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTACCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae D39	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae R6	96.917	100	0.969
comEC/celB	Streptococcus pneumoniae TIGR4	96.917	100	0.969
comEC/celB	Streptococcus mitis SK321	91.689	100	0.917
comEC/celB	Streptococcus mitis NCTC 12261	91.409	99.866	0.913
comEC	Lactococcus lactis subsp. cremoris KW2	44.399	99.33	0.441