Detailed information NTG0997317

Bioinformatically predicted

Overview

• Name: micA
• Type: Regulator
• Locus tag: ABC811_RS04275
• Genome accession: NZ_CP155535
• Coordinates: 831486..832190 (+)
• Length: 234 a.a.
• NCBI ID: WP_050144106.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PJ755/1
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 826486..837190

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC811_RS04250 (ABC811_04250)	coaC	826776..827327 (-)	552	WP_001284128.1	phosphopantothenoylcysteine decarboxylase	-
ABC811_RS04255 (ABC811_04255)	coaB	827339..828028 (-)	690	WP_000699494.1	phosphopantothenate--cysteine ligase	-
ABC811_RS04260 (ABC811_04260)	-	828258..829928 (+)	1671	WP_000845273.1	formate--tetrahydrofolate ligase	-
ABC811_RS04265 (ABC811_04265)	-	830034..830159 (-)	126	WP_001818232.1	hypothetical protein	-
ABC811_RS04270 (ABC811_04270)	mutY	830256..831431 (+)	1176	WP_000886148.1	A/G-specific adenine glycosylase	-
ABC811_RS04275 (ABC811_04275)	micA	831486..832190 (+)	705	WP_050144106.1	response regulator YycF	Regulator
ABC811_RS04280 (ABC811_04280)	micB	832183..833532 (+)	1350	WP_000886210.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ABC811_RS04285 (ABC811_04285)	vicX	833534..834343 (+)	810	WP_001289493.1	MBL fold metallo-hydrolase	Regulator
ABC811_RS04290 (ABC811_04290)	relB	834434..834676 (+)	243	WP_000208080.1	type II toxin-antitoxin system RelB family antitoxin	-
ABC811_RS04295 (ABC811_04295)	-	834678..834932 (+)	255	WP_001809704.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ABC811_RS04300 (ABC811_04300)	-	834979..835752 (+)	774	WP_000731131.1	ion transporter	-
ABC811_RS04305 (ABC811_04305)	-	836012..836998 (-)	987	WP_000204724.1	L-lactate dehydrogenase	-

Sequence

Protein

• Length: 234 a.a.
• Molecular weight: 26739.53 Da
• Isoelectric Point: 4.7164

>NTDB_id=997317 ABC811_RS04275 WP_050144106.1 831486..832190(+) (micA) [Streptococcus pneumoniae strain PJ755/1]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKSGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide

• Length: 705 bp

>NTDB_id=997317 ABC811_RS04275 WP_050144106.1 831486..832190(+) (micA) [Streptococcus pneumoniae strain PJ755/1]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATCTGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (154-229)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micA	Streptococcus pneumoniae Cp1015	99.573	100	0.996
vicR	Streptococcus mutans UA159	78.541	99.573	0.782
covR	Streptococcus salivarius strain HSISS4	44.156	98.718	0.436
covR	Lactococcus lactis subsp. lactis strain DGCC12653	43.478	98.291	0.427
scnR	Streptococcus mutans UA159	37.553	100	0.38