Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   HAS68_RS05480 Genome accession   NZ_CP002007
Coordinates   1074140..1074811 (+) Length   223 a.a.
NCBI ID   WP_009909965.1    Uniprot ID   -
Organism   Streptococcus suis 05HAS68     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1069140..1079811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HAS68_RS05455 (HAS68_0989) pstB 1069519..1070322 (+) 804 WP_002937615.1 phosphate ABC transporter ATP-binding protein PstB -
  HAS68_RS05460 (HAS68_0990) pstB 1070334..1071092 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  HAS68_RS05465 (HAS68_0991) phoU 1071121..1071777 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  HAS68_RS05470 (HAS68_0992) - 1071979..1073181 (-) 1203 WP_009909264.1 IS110-like element ISSsu7 family transposase -
  HAS68_RS05475 (HAS68_0993) - 1073566..1073946 (+) 381 WP_002935294.1 hypothetical protein -
  HAS68_RS05480 (HAS68_0994) ciaR 1074140..1074811 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  HAS68_RS05485 (HAS68_0995) ciaH 1074804..1076183 (+) 1380 WP_002935290.1 HAMP domain-containing sensor histidine kinase Regulator
  HAS68_RS05490 (HAS68_0996) - 1076507..1077619 (+) 1113 WP_238580470.1 transglutaminase domain-containing protein -
  HAS68_RS05495 (HAS68_0997) rpsT 1077995..1078243 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  HAS68_RS05500 (HAS68_0998) coaA 1078302..1079222 (-) 921 WP_002935283.1 type I pantothenate kinase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25290.00 Da        Isoelectric Point: 4.2183

>NTDB_id=99546 HAS68_RS05480 WP_009909965.1 1074140..1074811(+) (ciaR) [Streptococcus suis 05HAS68]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=99546 HAS68_RS05480 WP_009909965.1 1074140..1074811(+) (ciaR) [Streptococcus suis 05HAS68]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAATTACGTGAAAAAGGTGTTACGACACCTGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.135

100

0.901
  ciaR Streptococcus pneumoniae Rx1

88.341

100

0.883
  ciaR Streptococcus pneumoniae D39

88.341

100

0.883
  ciaR Streptococcus pneumoniae R6

88.341

100

0.883
  ciaR Streptococcus pneumoniae TIGR4

88.341

100

0.883
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.496

100

0.39
  vicR Streptococcus mutans UA159

35.47

100

0.372
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.363

Multiple sequence alignment