Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   AAFU62_RS06635 Genome accession   NZ_CP154891
Coordinates   1362259..1362969 (-) Length   236 a.a.
NCBI ID   WP_136268258.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 318231     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1357259..1367969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFU62_RS06620 (AAFU62_06620) rnc 1358966..1359658 (-) 693 WP_002990670.1 ribonuclease III -
  AAFU62_RS06625 (AAFU62_06625) vicX 1360101..1360910 (-) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  AAFU62_RS06630 (AAFU62_06630) vicK 1360914..1362266 (-) 1353 WP_002990673.1 cell wall metabolism sensor histidine kinase VicK Regulator
  AAFU62_RS06635 (AAFU62_06635) vicR 1362259..1362969 (-) 711 WP_136268258.1 response regulator YycF Regulator
  AAFU62_RS06640 (AAFU62_06640) - 1363131..1364165 (-) 1035 WP_194118140.1 DUF3114 domain-containing protein -
  AAFU62_RS06645 (AAFU62_06645) - 1364221..1365468 (-) 1248 WP_136094309.1 AMP-binding protein -
  AAFU62_RS06650 (AAFU62_06650) - 1365425..1366573 (-) 1149 WP_136268257.1 acetyl-CoA C-acyltransferase -
  AAFU62_RS06655 (AAFU62_06655) - 1366968..1367117 (-) 150 WP_002990686.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27069.96 Da        Isoelectric Point: 4.8996

>NTDB_id=994657 AAFU62_RS06635 WP_136268258.1 1362259..1362969(-) (vicR) [Streptococcus pyogenes strain 318231]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFDEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=994657 AAFU62_RS06635 WP_136268258.1 1362259..1362969(-) (vicR) [Streptococcus pyogenes strain 318231]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGATATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGACGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCACGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGAACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ACACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.831

100

0.898
  micA Streptococcus pneumoniae Cp1015

78.632

99.153

0.78
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364

Multiple sequence alignment