Detailed information NTG0994650

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: AAFU62_RS04220
• Genome accession: NZ_CP154891
• Coordinates: 856915..857751 (-)
• Length: 278 a.a.
• NCBI ID: WP_136268308.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 318231
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 851915..862751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAFU62_RS04200 (AAFU62_04200)	-	852133..853125 (-)	993	Protein_766	D-lactate dehydrogenase	-
AAFU62_RS04205 (AAFU62_04205)	-	853140..853706 (-)	567	Protein_767	PTS sugar transporter subunit IIC	-
AAFU62_RS04210 (AAFU62_04210)	-	853746..854603 (+)	858	Protein_768	LysR family transcriptional regulator	-
AAFU62_RS04215 (AAFU62_04215)	topA	854679..856808 (-)	2130	WP_136268309.1	type I DNA topoisomerase	-
AAFU62_RS04220 (AAFU62_04220)	dprA	856915..857751 (-)	837	WP_136268308.1	DNA-processing protein DprA	Machinery gene
AAFU62_RS04225 (AAFU62_04225)	-	857816..858607 (-)	792	WP_136268307.1	ribonuclease HII	-
AAFU62_RS04230 (AAFU62_04230)	ylqF	858597..859445 (-)	849	WP_129321912.1	ribosome biogenesis GTPase YlqF	-
AAFU62_RS04235 (AAFU62_04235)	-	859664..860104 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
AAFU62_RS04240 (AAFU62_04240)	-	860101..860751 (+)	651	WP_129321914.1	hemolysin III family protein	-
AAFU62_RS04245 (AAFU62_04245)	-	860868..861779 (+)	912	WP_002989777.1	diacylglycerol kinase family protein	-
AAFU62_RS04250 (AAFU62_04250)	-	861829..862197 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.00 Da
• Isoelectric Point: 9.0552

>NTDB_id=994650 AAFU62_RS04220 WP_136268308.1 856915..857751(-) (dprA) [Streptococcus pyogenes strain 318231]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPTLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=994650 AAFU62_RS04220 WP_136268308.1 856915..857751(-) (dprA) [Streptococcus pyogenes strain 318231]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTACATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	56.475	100	0.565
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367