Detailed information NTG0994476

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AAYT23_RS08965
• Genome accession: NZ_CP154877
• Coordinates: 1744061..1745071 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 20234295
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1739061..1750071

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT23_RS08940 (AAYT23_08925)	-	1740361..1740654 (-)	294	WP_000977369.1	hypothetical protein	-
AAYT23_RS08945 (AAYT23_08930)	-	1740816..1741268 (+)	453	WP_000079148.1	universal stress protein	-
AAYT23_RS08950 (AAYT23_08935)	-	1741303..1742691 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
AAYT23_RS08955 (AAYT23_08940)	-	1742757..1743719 (+)	963	WP_001124779.1	asparaginase	-
AAYT23_RS08960 (AAYT23_08945)	-	1743716..1743997 (-)	282	WP_001092043.1	hypothetical protein	-
AAYT23_RS08965 (AAYT23_08950)	ccpA	1744061..1745071 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
AAYT23_RS08970 (AAYT23_08955)	-	1745496..1746095 (-)	600	WP_000866731.1	response regulator transcription factor	-
AAYT23_RS08975 (AAYT23_08960)	-	1746096..1747193 (-)	1098	WP_000893510.1	sensor histidine kinase	-
AAYT23_RS08980 (AAYT23_08965)	-	1747193..1747930 (-)	738	WP_000832829.1	ABC transporter permease	-
AAYT23_RS08985 (AAYT23_08970)	-	1747932..1748816 (-)	885	WP_000219357.1	ABC transporter ATP-binding protein	-
AAYT23_RS08990 (AAYT23_08975)	-	1748803..1748997 (-)	195	WP_000820180.1	hypothetical protein	-
AAYT23_RS08995 (AAYT23_08980)	-	1748994..1749200 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=994476 AAYT23_RS08965 WP_000990607.1 1744061..1745071(-) (ccpA) [Streptococcus pneumoniae strain 20234295]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=994476 AAYT23_RS08965 WP_000990607.1 1744061..1745071(-) (ccpA) [Streptococcus pneumoniae strain 20234295]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568