Detailed information NTG0994481

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: AAYT23_RS09265
• Genome accession: NZ_CP154877
• Coordinates: 1793006..1793467 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20234295
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1788006..1798467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT23_RS09230 (AAYT23_09215)	-	1788310..1789134 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
AAYT23_RS09235 (AAYT23_09220)	rnpA	1789109..1789480 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AAYT23_RS09240 (AAYT23_09225)	-	1789497..1789628 (-)	132	WP_000768904.1	hypothetical protein	-
AAYT23_RS09245 (AAYT23_09230)	-	1789629..1790819 (-)	1191	WP_000167753.1	acetate kinase	-
AAYT23_RS09250 (AAYT23_09235)	comYH	1790870..1791823 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
AAYT23_RS09255 (AAYT23_09240)	-	1791884..1792478 (-)	595	Protein_1795	class I SAM-dependent methyltransferase	-
AAYT23_RS09260 (AAYT23_09245)	comGG/cglG	1792615..1793028 (-)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
AAYT23_RS09265 (AAYT23_09250)	comGF/cglF	1793006..1793467 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
AAYT23_RS09270 (AAYT23_09255)	comGE/cglE	1793430..1793732 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AAYT23_RS09275 (AAYT23_09260)	comGD/cglD	1793695..1794099 (-)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
AAYT23_RS09280 (AAYT23_09265)	comGC/cglC	1794092..1794418 (-)	327	WP_000738631.1	comG operon protein ComGC	Machinery gene
AAYT23_RS09285 (AAYT23_09270)	comGB/cglB	1794420..1795436 (-)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
AAYT23_RS09290 (AAYT23_09275)	comGA/cglA/cilD	1795384..1796325 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
AAYT23_RS09295 (AAYT23_09280)	-	1796401..1796766 (-)	366	WP_000286415.1	DUF1033 family protein	-
AAYT23_RS09300 (AAYT23_09285)	-	1796917..1797975 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.40 Da
• Isoelectric Point: 8.0016

>NTDB_id=994481 AAYT23_RS09265 WP_000250540.1 1793006..1793467(-) (comGF/cglF) [Streptococcus pneumoniae strain 20234295]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=994481 AAYT23_RS09265 WP_000250540.1 1793006..1793467(-) (comGF/cglF) [Streptococcus pneumoniae strain 20234295]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus mitis NCTC 12261	92.157	100	0.922