Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   SP4011_RS11375 Genome accession   NZ_AP026968
Coordinates   2322486..2323811 (-) Length   441 a.a.
NCBI ID   WP_218757900.1    Uniprot ID   -
Organism   Streptococcus parapneumoniae strain SP4011     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2317486..2328811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP4011_RS11350 (SP4011_21950) - 2318182..2320824 (-) 2643 WP_338619372.1 YhgE/Pip domain-containing protein -
  SP4011_RS11355 (SP4011_21960) - 2320952..2321494 (+) 543 WP_338619373.1 TetR/AcrR family transcriptional regulator -
  SP4011_RS11370 (SP4011_21970) comE 2321737..2322489 (-) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  SP4011_RS11375 (SP4011_21980) comD/comD1 2322486..2323811 (-) 1326 WP_218757900.1 GHKL domain-containing protein Regulator
  SP4011_RS11380 (SP4011_21990) comC/comC1 2323832..2323957 (-) 126 WP_218757899.1 competence-stimulating peptide ComC Regulator
  SP4011_RS11390 (SP4011_22000) rlmH 2324240..2324719 (-) 480 WP_084367488.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SP4011_RS11395 (SP4011_22010) htrA 2324903..2326084 (+) 1182 WP_338619378.1 S1C family serine protease Regulator
  SP4011_RS11400 (SP4011_22020) spo0J 2326142..2326900 (+) 759 WP_338619379.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50883.23 Da        Isoelectric Point: 6.8872

>NTDB_id=99151 SP4011_RS11375 WP_218757900.1 2322486..2323811(-) (comD/comD1) [Streptococcus parapneumoniae strain SP4011]
MNLLGFGTVIVYFLIISYSYHLICKGQVNRRELYVFGAYTLLTAIALDFPLYLLNLDGLGIATFLFPLGLYSYFRWIKQY
ERDRGLFLSLLLALLYESTHNFLSVTFSSITGDNFVLQYHDPFFFVVTVLTYVVILKIIHYFHLELAYFDKDYLYPFLKK
VLFALLLLHTASFVSDMVSTVKHLNSFGSILSSIVFISLLLTFFAMNSHKEQMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGDLQEIDRVYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLNNVKELLNKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=99151 SP4011_RS11375 WP_218757900.1 2322486..2323811(-) (comD/comD1) [Streptococcus parapneumoniae strain SP4011]
ATGAATTTGCTTGGATTTGGGACAGTTATTGTTTATTTTTTAATTATTAGTTACAGTTACCATTTAATTTGTAAAGGTCA
AGTAAATAGAAGAGAACTATACGTTTTTGGTGCTTATACATTACTAACAGCAATAGCACTTGATTTTCCCTTATATCTTC
TAAATTTAGATGGGTTAGGGATTGCAACATTTTTATTTCCTTTGGGCTTATATTCCTATTTTCGATGGATTAAACAGTAT
GAGAGGGATAGAGGATTATTCCTAAGTTTACTACTAGCACTTTTATATGAGAGCACTCATAACTTTCTGTCCGTAACTTT
CTCTTCTATAACAGGAGATAATTTTGTTTTACAATATCATGACCCATTCTTTTTCGTTGTAACGGTATTGACTTATGTTG
TTATCTTAAAAATCATTCATTATTTCCATCTAGAACTAGCCTATTTTGATAAGGACTACCTTTATCCTTTCTTGAAAAAA
GTATTGTTTGCTTTACTACTGCTCCATACTGCATCTTTCGTTTCAGATATGGTAAGTACGGTTAAACATTTGAATAGTTT
TGGAAGTATTTTGTCATCTATTGTCTTTATTTCTCTCCTTTTGACCTTCTTTGCAATGAATTCGCATAAAGAACAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAAAACTATACAGACGAAATTGTCGGACTGTAT
AATGAAATCCGTGGTTTTCGACATGACTATGCTGGAATGCTTGTCAGTATGCAGATGGCAATTGACAGTGGTGATTTACA
GGAAATTGACAGAGTTTACAATGAAGTTTTGGTCAAAGCCAATCATAAACTGCGTTCAGATAAGTACACTTACTTTGATT
TGAACAACATAGAAGATTCAGCTTTACGAAGTTTGGTTGCTCAGTCCATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTCCCAATCGAACTATTGGATTTGGTTCGTATCATGAGTGTTTTATTGAA
CAATGCTGTTGAAGGTTCAGCTGATAGCTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTTA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCCTTAGGATTCTCTACTAAGGGAAGA
AATCGCGGAGTCGGATTAAATAATGTAAAAGAACTACTAAATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATTATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus pneumoniae Rx1

93.197

100

0.932
  comD/comD1 Streptococcus pneumoniae D39

93.197

100

0.932
  comD/comD1 Streptococcus pneumoniae R6

93.197

100

0.932
  comD/comD2 Streptococcus pneumoniae TIGR4

92.744

100

0.927
  comD Streptococcus mitis SK321

91.837

100

0.918
  comD Streptococcus mitis NCTC 12261

85.034

100

0.85
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.211

86.168

0.424
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.947

86.168

0.422

Multiple sequence alignment