Detailed information NTG0099114

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SP4011_RS04955
• Genome accession: NZ_AP026968
• Coordinates: 961907..962755 (+)
• Length: 282 a.a.
• NCBI ID: WP_173212512.1
• Uniprot ID: -
• Organism: Streptococcus parapneumoniae strain SP4011
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 956907..967755

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP4011_RS04940 (SP4011_09070)	-	957618..958364 (+)	747	WP_173250101.1	N-acetylmuramoyl-L-alanine amidase	-
SP4011_RS04945 (SP4011_09080)	-	958384..958608 (+)	225	WP_338620149.1	YSIRK-type signal peptide-containing protein	-
SP4011_RS04950 (SP4011_09090)	-	958833..961685 (+)	2853	WP_338620150.1	hypothetical protein	-
SP4011_RS04955 (SP4011_09100)	dprA/cilB/dalA	961907..962755 (+)	849	WP_173212512.1	DNA-processing protein DprA	Machinery gene
SP4011_RS04960 (SP4011_09110)	-	963349..963501 (+)	153	WP_240149563.1	hypothetical protein	-
SP4011_RS04965 (SP4011_09120)	-	963570..964613 (+)	1044	WP_173212514.1	TIGR00341 family protein	-
SP4011_RS04970 (SP4011_09130)	topA	964780..966867 (+)	2088	WP_173212517.1	type I DNA topoisomerase	-
SP4011_RS04975 (SP4011_09140)	-	967124..967483 (+)	360	WP_001237210.1	YbaN family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31067.70 Da
• Isoelectric Point: 5.3986

>NTDB_id=99114 SP4011_RS04955 WP_173212512.1 961907..962755(+) (dprA/cilB/dalA) [Streptococcus parapneumoniae strain SP4011]
MKITNYEIYKLKKSGLSNQQILKVLEYGESVDQELLLGDIADISGCRNPAVFMERYFQIDDSHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDHIGNDHLILSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=99114 SP4011_RS04955 WP_173212512.1 961907..962755(+) (dprA/cilB/dalA) [Streptococcus parapneumoniae strain SP4011]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGAGCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAGTGTTGATCAAGAACTTTTGTTGGGTGACATTGCAGATATATCAGGTTGCCGAAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGATGATTCGCATTTGGAGAAAGAATTTCAAAAATTTCCATCTTTCTCTATTTTAGACGACTGT
TATCCTTGGGATTTGAGTGAAATATACGACGCGCCTGTGCTTTTATTTTACAAGGGAAATCTGGACCTCTTGAAATTCCC
GAAGGTAGCAGTCGTAGGAAGTCGTGCTTGTAGCAAACAGGGCGCTAAGTCAGTTGAAAAAGTCATTCAGGGCTTGGAAA
ATGAACTGGTTATCGTCAGTGGATTAGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTCCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACCACATCGGCAATGA
TCATCTGATTCTCAGTGAGTATGGACCTGGTGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATTATTGCTG
GACTTTGCCGTGGTGTGATTGTAGCAGAGGCCAAGATGCGCTCAGGTAGTCTCATTACCTGTGAGAGAGCAATGGAGGAA
GGGCGCGATGTCTTTGCTATACCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGGGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	97.872	100	0.979
dprA/cilB/dalA	Streptococcus pneumoniae D39	97.872	100	0.979
dprA/cilB/dalA	Streptococcus pneumoniae R6	97.872	100	0.979
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.163	100	0.972
dprA/cilB/dalA	Streptococcus mitis SK321	96.454	100	0.965
dprA	Streptococcus mutans UA159	62.5	99.291	0.621
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.291	0.543
dprA	Haemophilus influenzae Rd KW20	38.577	94.681	0.365