Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AAFQ93_RS08060 Genome accession   NZ_CP152419
Coordinates   1683223..1683894 (-) Length   223 a.a.
NCBI ID   WP_375555131.1    Uniprot ID   -
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1678223..1688894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS08035 (AAFQ93_07975) - 1678430..1679641 (-) 1212 WP_375555127.1 phosphopentomutase -
  AAFQ93_RS08040 (AAFQ93_07980) rpiA 1679654..1680337 (-) 684 WP_075227727.1 ribose-5-phosphate isomerase RpiA -
  AAFQ93_RS08045 (AAFQ93_07985) - 1680443..1681372 (-) 930 WP_375555128.1 peptidase U32 family protein -
  AAFQ93_RS08050 (AAFQ93_07990) - 1681511..1681786 (+) 276 WP_375555129.1 DUF3270 family protein -
  AAFQ93_RS08055 (AAFQ93_07995) ciaH 1681896..1683230 (-) 1335 WP_375555130.1 sensor histidine kinase Regulator
  AAFQ93_RS08060 (AAFQ93_08000) ciaR 1683223..1683894 (-) 672 WP_375555131.1 response regulator transcription factor Regulator
  AAFQ93_RS08065 (AAFQ93_08005) - 1684010..1686556 (-) 2547 WP_375555132.1 M1 family metallopeptidase -
  AAFQ93_RS08070 (AAFQ93_08010) - 1686679..1687119 (-) 441 WP_375555133.1 ASCH domain-containing protein -
  AAFQ93_RS08075 (AAFQ93_08015) - 1687064..1687963 (-) 900 WP_375555134.1 putative PEP-binding protein -
  AAFQ93_RS08080 (AAFQ93_08020) - 1687941..1688441 (-) 501 WP_223139900.1 NUDIX hydrolase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25334.13 Da        Isoelectric Point: 4.3826

>NTDB_id=989184 AAFQ93_RS08060 WP_375555131.1 1683223..1683894(-) (ciaR) [Streptococcus nidrosiense strain SO-23-1]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGISTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEEIKMRIQALLKRSGKFNENTLSYGDLTVNLSTNEVKVNDTVVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGSVFAENLQTLRSVGYILKHV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=989184 AAFQ93_RS08060 WP_375555131.1 1683223..1683894(-) (ciaR) [Streptococcus nidrosiense strain SO-23-1]
ATGATCAAAATTCTATTAGTAGAAGATGACCTAGGCCTATCAAATTCAGTCTTTGATTTTTTGGATGATTTTGCGGATGT
CATGCAGGTTTTTGATGGCGAAGAAGGTCTTTATGAGGCCGAAAGTGGTGTTTATGACTTGATTTTATTGGACTTGATGT
TACCTGAGAAAAATGGGTTTCAAGTTTTAAAAGAATTGCGTGAAAAAGGGATTTCAACTCCAGTTCTCATCATGACAGCC
AAGGAAAGTCTTGATGATAAGGGACATGGATTTGAGCTTGGAGCAGATGATTATCTAACAAAACCATTTTATCTAGAAGA
GATCAAGATGCGTATCCAAGCGCTGCTCAAACGTTCTGGTAAGTTCAATGAAAATACCCTCTCTTATGGTGATTTGACAG
TTAATCTATCTACAAATGAAGTTAAAGTCAATGATACTGTTGTGGAATTATTAGGTAAAGAATTTGATCTCTTGGTTTAT
TTCCTCCAAAACCAAAATGTGATCTTACCAAAAACACAGATTTTTGACCGTTTGTGGGGATTTGACAGTGACACAACCAT
CTCCGTGGTAGAAGTCTATGTATCAAAAGTTCGTAAGAAATTAAAGGGCTCAGTCTTTGCTGAAAACCTCCAGACCTTGC
GTAGTGTTGGGTATATTTTAAAACATGTTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

94.17

100

0.942
  ciaR Streptococcus pneumoniae D39

94.17

100

0.942
  ciaR Streptococcus pneumoniae R6

94.17

100

0.942
  ciaR Streptococcus pneumoniae TIGR4

94.17

100

0.942
  ciaR Streptococcus mutans UA159

88.235

99.103

0.874
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.333

100

0.377
  vicR Streptococcus mutans UA159

35.622

100

0.372

Multiple sequence alignment