Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   AAFQ93_RS08055 Genome accession   NZ_CP152419
Coordinates   1681896..1683230 (-) Length   444 a.a.
NCBI ID   WP_375555130.1    Uniprot ID   -
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1676896..1688230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS08025 (AAFQ93_07965) - 1677062..1677871 (-) 810 WP_375555125.1 purine-nucleoside phosphorylase -
  AAFQ93_RS08030 (AAFQ93_07970) - 1677868..1678428 (-) 561 WP_375555126.1 DUF1697 domain-containing protein -
  AAFQ93_RS08035 (AAFQ93_07975) - 1678430..1679641 (-) 1212 WP_375555127.1 phosphopentomutase -
  AAFQ93_RS08040 (AAFQ93_07980) rpiA 1679654..1680337 (-) 684 WP_075227727.1 ribose-5-phosphate isomerase RpiA -
  AAFQ93_RS08045 (AAFQ93_07985) - 1680443..1681372 (-) 930 WP_375555128.1 peptidase U32 family protein -
  AAFQ93_RS08050 (AAFQ93_07990) - 1681511..1681786 (+) 276 WP_375555129.1 DUF3270 family protein -
  AAFQ93_RS08055 (AAFQ93_07995) ciaH 1681896..1683230 (-) 1335 WP_375555130.1 sensor histidine kinase Regulator
  AAFQ93_RS08060 (AAFQ93_08000) ciaR 1683223..1683894 (-) 672 WP_375555131.1 response regulator transcription factor Regulator
  AAFQ93_RS08065 (AAFQ93_08005) - 1684010..1686556 (-) 2547 WP_375555132.1 M1 family metallopeptidase -
  AAFQ93_RS08070 (AAFQ93_08010) - 1686679..1687119 (-) 441 WP_375555133.1 ASCH domain-containing protein -
  AAFQ93_RS08075 (AAFQ93_08015) - 1687064..1687963 (-) 900 WP_375555134.1 putative PEP-binding protein -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 50488.03 Da        Isoelectric Point: 9.1973

>NTDB_id=989183 AAFQ93_RS08055 WP_375555130.1 1681896..1683230(-) (ciaH) [Streptococcus nidrosiense strain SO-23-1]
MFKKIKKNWYAEDFSYFIRNFGVFTLIFSAMTLIILQVMHSSLYTSVDEKLLSLSKNPQDVIQLAVNRATEDVKDLGSAN
VAPASDKKPTVSSNTEVILLDSNLNQLVTGNRFLGLDKITFNKKDLNHIRQLHVQNSYGQDEIYRVILSEINIDSVSTNI
KYAAVLINTSQIEQISQNHEQLIVVVMASFWILSIIASLYLARVSVKPLLESMQKQQSFVENASHELRTPLAVLQNRLET
LFRKPEATIMESSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPELGEVEPDFFNTTFTNYEMIASENNRVFHFENRIH
RTIITDKLLLKQLMTILFDNAVKYTEEEGDIHFVIATTERNLYLSVADDGIGISAVDKKKIFDRFYRVDKARTRQKGGFG
LGLSLAKQIVDALKGTISVKDNKPHGTIFEVKIAIQTPSKRKNK

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=989183 AAFQ93_RS08055 WP_375555130.1 1681896..1683230(-) (ciaH) [Streptococcus nidrosiense strain SO-23-1]
ATGTTTAAAAAAATTAAAAAGAATTGGTATGCGGAGGATTTTAGTTATTTTATCCGTAACTTTGGAGTATTTACTCTGAT
TTTCTCTGCTATGACCTTGATTATCTTACAGGTTATGCACTCCAGTCTCTACACATCGGTGGATGAAAAACTCTTATCAC
TGAGCAAAAATCCTCAAGACGTTATTCAATTGGCGGTCAATCGTGCAACTGAGGACGTTAAGGATTTAGGTAGTGCCAAT
GTTGCTCCAGCTTCTGATAAAAAACCAACGGTTAGTTCCAATACGGAAGTGATATTGCTAGATTCAAATTTGAATCAATT
AGTGACTGGCAACCGCTTTTTAGGGCTTGACAAGATCACTTTTAATAAAAAGGATTTGAATCATATTCGACAACTTCATG
TTCAGAATAGTTATGGTCAGGACGAGATTTACCGAGTGATTCTATCTGAAATAAATATCGATTCTGTCTCGACCAATATT
AAGTATGCAGCGGTTTTGATAAATACCAGTCAGATAGAGCAAATTAGTCAAAATCATGAGCAATTAATCGTGGTAGTCAT
GGCTAGCTTCTGGATTTTATCCATTATTGCCAGCCTTTATCTTGCGCGTGTCAGTGTTAAACCTTTACTTGAAAGCATGC
AAAAGCAACAGAGTTTTGTGGAAAATGCCAGTCATGAGCTACGAACTCCATTAGCTGTTCTGCAAAATCGTCTAGAAACT
CTTTTCAGAAAACCTGAGGCAACTATTATGGAGTCAAGTGAGAGTATTGCTTCCAGTCTAGAAGAAGTTCGTAATATGCG
CTTTTTAACGACTAATCTCCTTAATTTAGCTCGTCGTGATGACGGCATTAAACCGGAATTAGGAGAGGTAGAGCCAGATT
TCTTTAACACAACTTTTACCAACTATGAGATGATCGCATCTGAAAATAACCGCGTTTTTCATTTTGAAAATCGTATCCAT
CGGACCATCATAACAGATAAGCTTCTTCTTAAACAACTGATGACTATCTTGTTTGACAATGCTGTCAAGTACACAGAAGA
AGAAGGAGATATCCATTTTGTCATTGCTACGACGGAGCGTAATCTCTATTTGTCAGTAGCTGATGATGGAATTGGTATTT
CTGCAGTAGATAAAAAGAAAATTTTTGATCGCTTTTACAGGGTTGATAAGGCTCGTACTCGGCAAAAAGGTGGTTTTGGG
TTAGGCTTATCCTTAGCAAAACAGATTGTCGATGCTCTTAAAGGAACCATCAGTGTCAAAGATAACAAACCTCATGGTAC
GATTTTTGAAGTAAAAATCGCTATCCAAACACCATCCAAGCGTAAAAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(216-282)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

82.844

99.775

0.827
  ciaH Streptococcus pneumoniae D39

82.844

99.775

0.827
  ciaH Streptococcus pneumoniae R6

82.844

99.775

0.827
  ciaH Streptococcus pneumoniae TIGR4

82.844

99.775

0.827
  ciaH Streptococcus mutans UA159

55.963

98.198

0.55

Multiple sequence alignment