Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   AAFQ93_RS01655 Genome accession   NZ_CP152419
Coordinates   348733..350886 (-) Length   717 a.a.
NCBI ID   WP_375555448.1    Uniprot ID   -
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 343733..355886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS01645 (AAFQ93_01645) purC 346504..347211 (-) 708 WP_375555447.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  AAFQ93_RS01650 (AAFQ93_01650) comB 347380..348720 (-) 1341 WP_001190313.1 bacteriocin secretion accessory protein Regulator
  AAFQ93_RS01655 (AAFQ93_01655) comA 348733..350886 (-) 2154 WP_375555448.1 peptide cleavage/export ABC transporter ComA Regulator
  AAFQ93_RS01660 (AAFQ93_01665) - 351240..351476 (-) 237 WP_223140350.1 hypothetical protein -
  AAFQ93_RS01665 (AAFQ93_01670) - 351583..351792 (-) 210 WP_223140351.1 bacteriocin immunity protein -
  AAFQ93_RS01670 (AAFQ93_01675) - 351817..352005 (-) 189 WP_049531126.1 hypothetical protein -
  AAFQ93_RS01675 (AAFQ93_01680) - 352045..352215 (-) 171 WP_000067700.1 H354_08695 family bacteriocin-like peptide -
  AAFQ93_RS01680 (AAFQ93_01685) - 352447..352623 (-) 177 WP_049526785.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  AAFQ93_RS01685 (AAFQ93_01690) - 353198..353434 (-) 237 WP_000130002.1 acyl carrier protein -
  AAFQ93_RS01690 (AAFQ93_01695) plsX 353440..354432 (-) 993 WP_223140352.1 phosphate acyltransferase PlsX -
  AAFQ93_RS01695 (AAFQ93_01700) recO 354429..355199 (-) 771 WP_075226983.1 DNA repair protein RecO -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80391.43 Da        Isoelectric Point: 6.3095

>NTDB_id=989147 AAFQ93_RS01655 WP_375555448.1 348733..350886(-) (comA) [Streptococcus nidrosiense strain SO-23-1]
MKFSKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDV
TFPFVAHVLKEGKLLHYYVVTGQDKNNIYIADPDPSVKLTKISRERFAKEWTGITIFMAPSPSYKPHKEQKNGLLSFIPI
LVKQRGLIVNIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYVLQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVLIISVVLFSQNSNLFFMSLLALPIYTV
IIFAFMKPFEKMNRETMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVDYLKKSFTYSRAESQQKALKKLAQL
LLNVAILWMGALLVMDNKMSLGQLITYNTLLIYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVSDLSLL
EGDMDFKQVHYKYGYGRDVLSDIDLTIAQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGTHMELLAQGGFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=989147 AAFQ93_RS01655 WP_375555448.1 348733..350886(-) (comA) [Streptococcus nidrosiense strain SO-23-1]
ATGAAATTTAGTAAACGGCATTATCGTCCTCAGGTAGACCAGATGGACTGTGGTGTGGCTTCATTAGCCATGGTCTTTGG
TTATTATGGTAGTTATTATTCTCTGGCTCACTTGCGAGAGTTGGCCAAGACGACCATGGATGGGACTACGGCTTTAGGTT
TAGTCAAGGTTGCTGAGGAGATAGGTTTTGAGACGCGAGCAATAAAGGCGGACATGACCTTGTTTGATTTGCCGGATGTA
ACTTTTCCTTTTGTGGCTCATGTGCTTAAGGAAGGGAAATTGCTCCATTATTATGTGGTGACTGGCCAGGACAAGAACAA
CATTTATATTGCTGATCCAGATCCTAGTGTTAAGCTGACCAAGATTTCTCGTGAACGCTTTGCCAAGGAGTGGACAGGAA
TCACTATTTTTATGGCACCATCTCCGAGTTATAAGCCTCATAAGGAACAAAAAAATGGTCTGCTATCCTTTATCCCTATA
TTAGTGAAACAGCGAGGTTTGATTGTTAATATCGTTTTGGCGACCCTCTTGGTGACCTTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACTTATGTACCAGATCAGATGCGCTCGACACTGGGAATTATTTCGATAGGGCTAGTCA
TCGTTTATGTCCTTCAGCAAATCTTATCTTATGCCCAGGAGTATCTTTTACTTGTTTTGGGGCAACGCTTGTCCATTGAT
GTGATTTTGTCCTATATCAAGCACGTTTTCCATCTACCCATGTCCTTTTTTGCAACACGAAGGACAGGGGAAATCGTGTC
TCGTTTCACGGATGCAAATAGTATCATCGATGCGCTGGCTTCGACTATTCTGTCAATCTTTTTGGATGTATCTACTGTCT
TGATTATTTCAGTAGTTCTATTTTCGCAGAATAGCAATCTCTTTTTCATGAGTTTACTAGCCCTTCCTATCTACACAGTG
ATTATCTTTGCTTTTATGAAGCCCTTTGAAAAGATGAATCGGGAAACTATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAATGGCATTGAGACCATCAAGTCCTTAACTAGTGAAAGTTCACGCTACCAAAAGATTGACAAGGAAT
TTGTAGATTATCTGAAAAAATCTTTTACTTACAGTCGGGCAGAAAGTCAGCAAAAGGCTCTGAAAAAGCTTGCCCAACTC
TTGCTCAATGTTGCCATTCTCTGGATGGGGGCTCTCCTAGTCATGGATAATAAGATGAGTTTGGGCCAGTTGATTACCTA
TAATACCTTGCTTATTTACTTTACAAATCCATTGGAAAATATCATCAACCTGCAAACCAAACTTCAGACAGCGCAGGTAG
CCAATAACCGTCTCAATGAAGTTTATCTGGTTGCATCTGAGTTTGAGGAAAAGAAAACAGTCTCAGATTTGAGCTTGCTA
GAAGGAGATATGGATTTCAAGCAGGTTCACTACAAATATGGCTATGGCCGAGATGTCTTGTCGGACATCGATCTAACCAT
TGCGCAAGGCTCTAAAGTGGCTTTTGTAGGGATTTCAGGATCGGGTAAGACGACCTTGGCTAAGATGATGGTTAATTTTT
ATGATCCAAGTCAGGGGGAGATTAGCCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAGGCTCTGCGCCAGTATATC
AACTACCTGCCTCAGCAGCCCTACGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTCGGAGCTAAGGAGGGGACGAC
CCAGGAGGATATCTTGAGAGCAGTGGAGTTGGCAGAGATTCGGGAGGATATTGAGCGCATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGAGCGGGCATTTCAGGTGGGCAACGTCAGAGGATCGCTTTGGCGCGTGCTCTATTGACCGATGCG
CCTGTCTTGATCTTGGATGAGGCGACCAGCAGTCTAGATATTTTGACCGAGAAGCGAATTGTCGATAATCTGATGGCTTT
AGATAAGACCTTGATTTTCATCGCCCACCGTTTAACCATTGCTGAGCGGACAGAGAAGGTTGTCGTTTTGGATCAGGGAA
AGATTGTCGAAGAGGGTACACATATGGAATTACTGGCTCAGGGTGGTTTCTATGCCCACTTGGTGAATAGTTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae Rx1

94.421

100

0.944
  comA Streptococcus pneumoniae D39

94.421

100

0.944
  comA Streptococcus pneumoniae R6

94.421

100

0.944
  comA Streptococcus mitis NCTC 12261

94.421

100

0.944
  comA Streptococcus mitis SK321

94.142

100

0.941
  comA Streptococcus pneumoniae TIGR4

94.003

100

0.94
  comA Streptococcus gordonii str. Challis substr. CH1

81.59

100

0.816
  comA/nlmT Streptococcus mutans UA159

66.109

100

0.661

Multiple sequence alignment