Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   AAFQ93_RS01650 Genome accession   NZ_CP152419
Coordinates   347380..348720 (-) Length   446 a.a.
NCBI ID   WP_001190313.1    Uniprot ID   I2JB98
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 342380..353720
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS01640 (AAFQ93_01640) - 342715..346440 (-) 3726 WP_375555446.1 phosphoribosylformylglycinamidine synthase -
  AAFQ93_RS01645 (AAFQ93_01645) purC 346504..347211 (-) 708 WP_375555447.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  AAFQ93_RS01650 (AAFQ93_01650) comB 347380..348720 (-) 1341 WP_001190313.1 bacteriocin secretion accessory protein Regulator
  AAFQ93_RS01655 (AAFQ93_01655) comA 348733..350886 (-) 2154 WP_375555448.1 peptide cleavage/export ABC transporter ComA Regulator
  AAFQ93_RS01660 (AAFQ93_01665) - 351240..351476 (-) 237 WP_223140350.1 hypothetical protein -
  AAFQ93_RS01665 (AAFQ93_01670) - 351583..351792 (-) 210 WP_223140351.1 bacteriocin immunity protein -
  AAFQ93_RS01670 (AAFQ93_01675) - 351817..352005 (-) 189 WP_049531126.1 hypothetical protein -
  AAFQ93_RS01675 (AAFQ93_01680) - 352045..352215 (-) 171 WP_000067700.1 H354_08695 family bacteriocin-like peptide -
  AAFQ93_RS01680 (AAFQ93_01685) - 352447..352623 (-) 177 WP_049526785.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  AAFQ93_RS01685 (AAFQ93_01690) - 353198..353434 (-) 237 WP_000130002.1 acyl carrier protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 49499.53 Da        Isoelectric Point: 5.7145

>NTDB_id=989146 AAFQ93_RS01650 WP_001190313.1 347380..348720(-) (comB) [Streptococcus nidrosiense strain SO-23-1]
MQSEFLESAEFYNRRYHNFSSYVIFPSFILFLFLIVFSIFAQKEISLTAGATVEPARIIATIQSSSNSKIVANHLAENKF
VKQGDLLVQYQEGAEAVQAENYASQLEMLKDQKVQLEYLKASLQAGSDQFPEADKFGYQHSFLDYLNQVASLRSQVEQQN
ASISSQNAAASGSQAELGNLIGETQSKIKEYQQAKSAIQGDGHLESDHPAYAIYQSTKEQGSETKQQALSQLDAQITQLE
STLAGYRVQYAGSGAQQAYASGLGSQLESLKSQQLAKVGQELTLLDQKILEAESGKKIQGNLLEKEKITATEDGVLHLNP
EHSRSTIIPEGTILAHLFPQLARERKAKLTAYISSKEVAGLKPGNEVRFTTVTDANKQLVLTSKITNIDTSATQTEKGNF
FKLEAETDLNAEQAEKLRYGLEGRLTMITGRKSFLRYYLDRFLKQE

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=989146 AAFQ93_RS01650 WP_001190313.1 347380..348720(-) (comB) [Streptococcus nidrosiense strain SO-23-1]
ATGCAATCAGAATTTTTAGAAAGTGCTGAGTTTTACAATCGTCGTTACCATAATTTTTCTAGTTATGTGATTTTTCCAAG
TTTTATCTTGTTTTTGTTCCTGATCGTTTTTTCAATCTTTGCCCAAAAGGAGATAAGCTTGACAGCTGGAGCTACGGTAG
AACCTGCTCGTATCATTGCTACCATTCAGTCTAGTAGTAATAGTAAGATTGTGGCGAATCATTTGGCTGAAAATAAGTTT
GTCAAGCAAGGGGATCTTCTCGTTCAATACCAAGAGGGAGCAGAAGCCGTTCAGGCTGAGAATTATGCCAGTCAGTTGGA
AATGCTCAAGGATCAGAAGGTTCAACTGGAGTATTTAAAAGCAAGCCTTCAAGCAGGAAGTGATCAATTTCCAGAAGCAG
ATAAATTTGGCTATCAGCATAGTTTTTTAGATTATCTAAATCAAGTTGCTAGTTTACGGAGTCAGGTTGAGCAACAAAAT
GCTAGTATATCATCTCAAAATGCAGCAGCCAGTGGTAGTCAGGCAGAATTAGGCAATCTCATCGGAGAAACCCAGTCCAA
AATTAAAGAATATCAGCAAGCCAAGTCTGCTATTCAGGGTGATGGACACTTAGAGAGTGATCATCCAGCTTATGCTATTT
ATCAGTCGACAAAGGAGCAAGGATCGGAAACCAAACAGCAGGCCTTATCTCAGCTAGATGCTCAAATCACTCAGTTGGAG
TCAACTCTTGCAGGTTATCGAGTACAGTATGCAGGTTCAGGAGCCCAGCAAGCTTATGCATCTGGATTGGGAAGTCAGTT
GGAGTCATTAAAATCTCAGCAACTAGCCAAGGTAGGCCAGGAATTAACGCTCTTGGATCAGAAAATTCTTGAAGCGGAGT
CGGGTAAAAAGATTCAAGGGAATCTTTTAGAGAAGGAGAAAATTACAGCAACAGAAGATGGTGTTCTACATTTGAATCCT
GAGCATAGTCGATCTACCATCATTCCAGAAGGAACTATCCTCGCTCACCTTTTTCCGCAGTTGGCTAGAGAGAGGAAGGC
AAAACTGACAGCTTATATCAGTTCTAAGGAAGTGGCTGGTCTCAAGCCTGGAAATGAGGTACGATTTACAACGGTAACGG
ATGCCAATAAGCAGCTAGTGTTGACATCCAAGATTACGAATATCGATACCAGTGCGACTCAGACAGAAAAGGGCAATTTC
TTTAAATTAGAGGCAGAGACGGATTTGAATGCTGAACAAGCAGAAAAACTTCGTTATGGACTTGAAGGTCGTTTGACTAT
GATTACAGGTAGGAAGAGTTTTTTACGCTACTATCTTGACCGCTTTTTGAAACAAGAATAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(308-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2JB98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

68.374

100

0.688
  comB Streptococcus pneumoniae D39

68.374

100

0.688
  comB Streptococcus pneumoniae R6

68.374

100

0.688
  comB Streptococcus pneumoniae TIGR4

68.151

100

0.686
  comB Streptococcus mitis SK321

67.483

100

0.679
  comB Streptococcus mitis NCTC 12261

67.038

100

0.675
  comB Streptococcus gordonii str. Challis substr. CH1

53.898

100

0.543

Multiple sequence alignment