Detailed information NTG0098661

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R8615_RS04535
• Genome accession: NZ_AP026929
• Coordinates: 883545..884498 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain PZ900701114
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 878545..889498

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8615_RS04510	rpmG	879288..879437 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
R8615_RS04515 (PC1101_08980)	secG	879477..879710 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R8615_RS04520 (PC1101_08990)	rnr	879812..882166 (+)	2355	WP_024477774.1	ribonuclease R	-
R8615_RS04525 (PC1101_09000)	smpB	882129..882596 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R8615_RS04530 (PC1101_09010)	tehB	882612..883472 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
R8615_RS04535 (PC1101_09020)	coiA	883545..884498 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
R8615_RS04540 (PC1101_09030)	pepF	884517..886319 (+)	1803	WP_024477773.1	oligoendopeptidase F	Regulator
R8615_RS04545 (PC1101_09040)	-	886321..887034 (+)	714	WP_000230399.1	O-methyltransferase	-
R8615_RS04550 (PC1101_09050)	prsA	887101..888042 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R8615_RS04555 (PC1101_09060)	-	888161..888502 (-)	342	Protein_899	transposase	-
R8615_RS04560	-	888914..889009 (+)	96	Protein_900	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=98661 R8615_RS04535 WP_000495911.1 883545..884498(+) (coiA) [Streptococcus pneumoniae strain PZ900701114]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=98661 R8615_RS04535 WP_000495911.1 883545..884498(+) (coiA) [Streptococcus pneumoniae strain PZ900701114]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435