Detailed information NTG0098508

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: R8611_RS05735
• Genome accession: NZ_AP026927
• Coordinates: 1137260..1138108 (-)
• Length: 282 a.a.
• NCBI ID: WP_050255980.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700178
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1132260..1143108

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8611_RS05720 (PC0174_11240)	-	1132659..1133018 (-)	360	WP_001237218.1	YbaN family protein	-
R8611_RS05725 (PC0174_11250)	topA	1133124..1135211 (-)	2088	WP_000179642.1	type I DNA topoisomerase	-
R8611_RS05730 (PC0174_11260)	-	1135378..1136421 (-)	1044	WP_050255979.1	TIGR00341 family protein	-
R8611_RS05735 (PC0174_11270)	dprA/cilB/dalA	1137260..1138108 (-)	849	WP_050255980.1	DNA-processing protein DprA	Machinery gene
R8611_RS05740 (PC0174_11280)	-	1138204..1138893 (-)	690	WP_050148582.1	sugar phosphate nucleotidyltransferase	-
R8611_RS05745 (PC0174_11290)	-	1138905..1139783 (-)	879	WP_000837609.1	DMT family transporter	-
R8611_RS05750 (PC0174_11300)	licA	1139773..1140642 (-)	870	WP_000411207.1	choline kinase LicA	-
R8611_RS05755 (PC0174_11310)	-	1140659..1141681 (-)	1023	WP_050199519.1	ribitol-5-phosphate dehydrogenase	-
R8611_RS05760 (PC0174_11320)	-	1141686..1142393 (-)	708	WP_000638482.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31009.68 Da
• Isoelectric Point: 5.1976

>NTDB_id=98508 R8611_RS05735 WP_050255980.1 1137260..1138108(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain PZ900700178]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCCNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=98508 R8611_RS05735 WP_050255980.1 1137260..1138108(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain PZ900700178]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCTGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	63.214	99.291	0.628
dprA	Lactococcus lactis subsp. cremoris KW2	55.714	99.291	0.553
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362