Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8559_RS02825 Genome accession   NZ_AP026926
Coordinates   534130..535806 (-) Length   558 a.a.
NCBI ID   WP_196299874.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700119     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 529130..540806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8559_RS02795 (PC0116_05490) - 529462..529791 (-) 330 WP_000132583.1 hypothetical protein -
  R8559_RS02800 (PC0116_05500) - 530068..530406 (+) 339 WP_000682136.1 LytTR family DNA-binding domain-containing protein -
  R8559_RS02805 (PC0116_05510) comE/blpR 530411..531148 (+) 738 WP_001219136.1 LytTR family DNA-binding domain-containing protein Regulator
  R8559_RS02810 (PC0116_05520) - 531162..532502 (+) 1341 WP_001017643.1 sensor histidine kinase -
  R8559_RS02815 (PC0116_05530) blpC 532573..532701 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  R8559_RS02820 (PC0116_05540) - 532758..534119 (-) 1362 Protein_555 bacteriocin secretion accessory protein -
  R8559_RS02825 (PC0116_05560) comA/nlmT 534130..535806 (-) 1677 WP_196299874.1 peptide cleavage/export ABC transporter Regulator
  R8559_RS02830 (PC0116_05570) comA/nlmT 535700..536287 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8559_RS02835 (PC0116_05580) blpI 536569..536766 (+) 198 WP_001093261.1 bacteriocin-like peptide BlpI -
  R8559_RS02840 (PC0116_05600) blpJ 537233..537502 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  R8559_RS02845 (PC0116_05610) blpU 537571..537801 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  R8559_RS02850 - 537804..537923 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  R8559_RS02855 (PC0116_05620) - 538220..538384 (+) 165 WP_000727118.1 hypothetical protein -
  R8559_RS02860 (PC0116_05630) - 538381..538785 (+) 405 WP_000846944.1 hypothetical protein -
  R8559_RS02865 - 538988..539793 (+) 806 Protein_564 IS5 family transposase -
  R8559_RS02870 (PC0116_05660) blpM 539943..540197 (+) 255 WP_000379877.1 two-peptide bacteriocin subunit BlpM -
  R8559_RS02875 (PC0116_05670) blpN 540213..540416 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62923.20 Da        Isoelectric Point: 6.7844

>NTDB_id=98411 R8559_RS02825 WP_196299874.1 534130..535806(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700119]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=98411 R8559_RS02825 WP_196299874.1 534130..535806(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700119]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGATCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.89

99.821

0.728
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae D39

66.846

100

0.668
  comA Streptococcus pneumoniae R6

66.846

100

0.668
  comA Streptococcus pneumoniae Rx1

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667
  comA Streptococcus pneumoniae TIGR4

66.487

100

0.665

Multiple sequence alignment