Detailed information NTG0098063

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R9C51_RS10145
• Genome accession: NZ_AP026921
• Coordinates: 1945371..1945832 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700027
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1940371..1950832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R9C51_RS10110 (PC0027_19730)	-	1940675..1941499 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
R9C51_RS10115 (PC0027_19740)	rnpA	1941474..1941845 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R9C51_RS10120	-	1941862..1941993 (-)	132	WP_000768904.1	hypothetical protein	-
R9C51_RS10125 (PC0027_19750)	-	1941994..1943184 (-)	1191	WP_000167753.1	acetate kinase	-
R9C51_RS10130 (PC0027_19760)	comYH	1943235..1944188 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
R9C51_RS10135	-	1944249..1944843 (-)	595	Protein_1976	class I SAM-dependent methyltransferase	-
R9C51_RS10140 (PC0027_19790)	comGG/cglG	1944980..1945393 (-)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
R9C51_RS10145 (PC0027_19800)	comGF/cglF	1945371..1945832 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
R9C51_RS10150 (PC0027_19810)	comGE/cglE	1945795..1946097 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R9C51_RS10155 (PC0027_19820)	comGD/cglD	1946060..1946464 (-)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
R9C51_RS10160 (PC0027_19830)	comGC/cglC	1946457..1946783 (-)	327	WP_000738630.1	comG operon protein ComGC	Machinery gene
R9C51_RS10165 (PC0027_19840)	comGB/cglB	1946785..1947801 (-)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
R9C51_RS10170 (PC0027_19850)	comGA/cglA/cilD	1947749..1948690 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R9C51_RS10175 (PC0027_19860)	-	1948766..1949131 (-)	366	WP_000286415.1	DUF1033 family protein	-
R9C51_RS10180 (PC0027_19870)	-	1949282..1950340 (-)	1059	WP_000649466.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.40 Da
• Isoelectric Point: 8.0016

>NTDB_id=98063 R9C51_RS10145 WP_000250540.1 1945371..1945832(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700027]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=98063 R9C51_RS10145 WP_000250540.1 1945371..1945832(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700027]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus mitis NCTC 12261	92.157	100	0.922