Detailed information NTG0098018

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: R9C51_RS02875
• Genome accession: NZ_AP026921
• Coordinates: 540959..543112 (-)
• Length: 717 a.a.
• NCBI ID: WP_044727696.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700027
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 535959..548112

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R9C51_RS02845 (PC0027_05590)	-	536291..536620 (-)	330	WP_047499345.1	hypothetical protein	-
R9C51_RS02850 (PC0027_05600)	-	536897..537235 (+)	339	WP_000682121.1	LytTR family DNA-binding domain-containing protein	-
R9C51_RS02855 (PC0027_05610)	comE/blpR	537240..537977 (+)	738	WP_001219137.1	LytTR family DNA-binding domain-containing protein	Regulator
R9C51_RS02860 (PC0027_05620)	-	537991..539331 (+)	1341	WP_050273644.1	sensor histidine kinase	-
R9C51_RS02865 (PC0027_05630)	blpC	539375..539530 (-)	156	WP_000358811.1	quorum-sensing system pheromone BlpC	-
R9C51_RS02870 (PC0027_05640)	-	539587..540948 (-)	1362	WP_001865175.1	bacteriocin secretion accessory protein	-
R9C51_RS02875 (PC0027_05650)	comA/nlmT	540959..543112 (-)	2154	WP_044727696.1	peptide cleavage/export ABC transporter BlpA	Regulator
R9C51_RS02880 (PC0027_05660)	blpU	543393..543623 (+)	231	WP_001093268.1	bacteriocin-like peptide BlpU	-
R9C51_RS02885	-	543626..543745 (+)	120	WP_001829206.1	PncF family bacteriocin immunity protein	-
R9C51_RS02890 (PC0027_05680)	-	544214..544585 (+)	372	WP_033705507.1	hypothetical protein	-
R9C51_RS02895 (PC0027_05700)	-	545214..545597 (+)	384	WP_016398494.1	hypothetical protein	-
R9C51_RS02900 (PC0027_05710)	-	545649..546338 (+)	690	WP_050201633.1	CPBP family intramembrane glutamic endopeptidase	-
R9C51_RS02905 (PC0027_05720)	blpZ	546380..546613 (+)	234	WP_000276498.1	immunity protein BlpZ	-
R9C51_RS02910	-	546764..547375 (+)	612	WP_000394036.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80839.91 Da
• Isoelectric Point: 7.6798

>NTDB_id=98018 R9C51_RS02875 WP_044727696.1 540959..543112(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700027]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTIALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=98018 R9C51_RS02875 WP_044727696.1 540959..543112(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900700027]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGATTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGGCCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTA
CTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGTTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.028	99.721	0.718
comA	Streptococcus mitis NCTC 12261	66.62	99.442	0.662
comA	Streptococcus pneumoniae Rx1	66.059	99.442	0.657
comA	Streptococcus pneumoniae R6	66.059	99.442	0.657
comA	Streptococcus pneumoniae D39	66.059	99.442	0.657
comA	Streptococcus mitis SK321	66.059	99.442	0.657
comA	Streptococcus gordonii str. Challis substr. CH1	65.32	100	0.654
comA	Streptococcus pneumoniae TIGR4	65.778	99.442	0.654