Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   R9C51_RS02855 Genome accession   NZ_AP026921
Coordinates   537240..537977 (+) Length   245 a.a.
NCBI ID   WP_001219137.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700027     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 532240..542977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R9C51_RS02820 - 533215..533409 (-) 195 WP_001808905.1 hypothetical protein -
  R9C51_RS02825 (PC0027_05550) - 533571..533858 (-) 288 WP_000777760.1 hypothetical protein -
  R9C51_RS02830 (PC0027_05560) - 533868..534278 (-) 411 WP_001278301.1 HIT family protein -
  R9C51_RS02835 (PC0027_05570) pptA 534346..535077 (+) 732 WP_000889921.1 ABC transporter ATP-binding protein Regulator
  R9C51_RS02840 (PC0027_05580) - 535074..536123 (+) 1050 WP_000653771.1 ABC transporter permease -
  R9C51_RS02845 (PC0027_05590) - 536291..536620 (-) 330 WP_047499345.1 hypothetical protein -
  R9C51_RS02850 (PC0027_05600) - 536897..537235 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  R9C51_RS02855 (PC0027_05610) comE/blpR 537240..537977 (+) 738 WP_001219137.1 LytTR family DNA-binding domain-containing protein Regulator
  R9C51_RS02860 (PC0027_05620) - 537991..539331 (+) 1341 WP_050273644.1 sensor histidine kinase -
  R9C51_RS02865 (PC0027_05630) blpC 539375..539530 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  R9C51_RS02870 (PC0027_05640) - 539587..540948 (-) 1362 WP_001865175.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28768.92 Da        Isoelectric Point: 6.2366

>NTDB_id=98017 R9C51_RS02855 WP_001219137.1 537240..537977(+) (comE/blpR) [Streptococcus pneumoniae strain PZ900700027]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=98017 R9C51_RS02855 WP_001219137.1 537240..537977(+) (comE/blpR) [Streptococcus pneumoniae strain PZ900700027]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCTGAGTTCTTTTGAAGTTTTTGGTAAGCCAGATCAATTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.441

100

0.539
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment