Detailed information NTG0978493

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS37642_RS04600
• Genome accession: NZ_CP151468
• Coordinates: 903608..904444 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS37642
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 898608..909444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37642_RS04570 (MGAS37642_01886)	-	899162..899530 (+)	369	WP_010922310.1	hypothetical protein	-
MGAS37642_RS04575 (MGAS37642_01888)	-	899580..900491 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
MGAS37642_RS04580 (MGAS37642_01890)	-	900608..901258 (-)	651	WP_002984629.1	hemolysin III family protein	-
MGAS37642_RS04585 (MGAS37642_01892)	-	901255..901695 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
MGAS37642_RS04590 (MGAS37642_01894)	ylqF	901914..902762 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
MGAS37642_RS04595 (MGAS37642_01896)	-	902752..903543 (+)	792	WP_011285534.1	ribonuclease HII	-
MGAS37642_RS04600 (MGAS37642_01898)	dprA	903608..904444 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
MGAS37642_RS04605 (MGAS37642_01900)	topA	904551..906680 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
MGAS37642_RS04610	-	906755..907637 (-)	883	Protein_845	LysR family transcriptional regulator	-
MGAS37642_RS04615 (MGAS37642_01904)	-	907650..908195 (+)	546	Protein_846	PTS sugar transporter subunit IIC	-
MGAS37642_RS04620 (MGAS37642_01906)	-	908210..909202 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=978493 MGAS37642_RS04600 WP_010922314.1 903608..904444(+) (dprA) [Streptococcus pyogenes strain MGAS37642]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=978493 MGAS37642_RS04600 WP_010922314.1 903608..904444(+) (dprA) [Streptococcus pyogenes strain MGAS37642]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367