Detailed information NTG0978157

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS37826_RS04535
• Genome accession: NZ_CP151462
• Coordinates: 897605..898441 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS37826
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 892605..903441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37826_RS04505 (MGAS37826_01862)	-	893159..893527 (+)	369	WP_010922310.1	hypothetical protein	-
MGAS37826_RS04510 (MGAS37826_01864)	-	893577..894488 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
MGAS37826_RS04515 (MGAS37826_01866)	-	894605..895255 (-)	651	WP_002984629.1	hemolysin III family protein	-
MGAS37826_RS04520 (MGAS37826_01868)	-	895252..895692 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
MGAS37826_RS04525 (MGAS37826_01870)	ylqF	895911..896759 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
MGAS37826_RS04530 (MGAS37826_01872)	-	896749..897540 (+)	792	WP_011285534.1	ribonuclease HII	-
MGAS37826_RS04535 (MGAS37826_01874)	dprA	897605..898441 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
MGAS37826_RS04540 (MGAS37826_01876)	topA	898548..900677 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
MGAS37826_RS04545	-	900752..901634 (-)	883	Protein_845	LysR family transcriptional regulator	-
MGAS37826_RS04550 (MGAS37826_01880)	-	901647..902192 (+)	546	Protein_846	PTS sugar transporter subunit IIC	-
MGAS37826_RS04555 (MGAS37826_01882)	-	902207..903199 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=978157 MGAS37826_RS04535 WP_010922314.1 897605..898441(+) (dprA) [Streptococcus pyogenes strain MGAS37826]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=978157 MGAS37826_RS04535 WP_010922314.1 897605..898441(+) (dprA) [Streptococcus pyogenes strain MGAS37826]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367