Detailed information NTG0977318

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS37849_RS04535
• Genome accession: NZ_CP151447
• Coordinates: 897629..898465 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS37849
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 892629..903465

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37849_RS04505 (MGAS37849_01856)	-	893183..893551 (+)	369	WP_010922310.1	hypothetical protein	-
MGAS37849_RS04510 (MGAS37849_01858)	-	893601..894512 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
MGAS37849_RS04515 (MGAS37849_01860)	-	894629..895279 (-)	651	WP_002984629.1	hemolysin III family protein	-
MGAS37849_RS04520 (MGAS37849_01862)	-	895276..895716 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
MGAS37849_RS04525 (MGAS37849_01864)	ylqF	895935..896783 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
MGAS37849_RS04530 (MGAS37849_01866)	-	896773..897564 (+)	792	WP_011285534.1	ribonuclease HII	-
MGAS37849_RS04535 (MGAS37849_01868)	dprA	897629..898465 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
MGAS37849_RS04540 (MGAS37849_01870)	topA	898572..900701 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
MGAS37849_RS04545	-	900776..901658 (-)	883	Protein_845	LysR family transcriptional regulator	-
MGAS37849_RS04550 (MGAS37849_01874)	-	901671..902216 (+)	546	Protein_846	PTS sugar transporter subunit IIC	-
MGAS37849_RS04555 (MGAS37849_01876)	-	902231..903223 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=977318 MGAS37849_RS04535 WP_010922314.1 897629..898465(+) (dprA) [Streptococcus pyogenes strain MGAS37849]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=977318 MGAS37849_RS04535 WP_010922314.1 897629..898465(+) (dprA) [Streptococcus pyogenes strain MGAS37849]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367