Detailed information NTG0976926

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS38289_RS04470
• Genome accession: NZ_CP151440
• Coordinates: 891606..892442 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS38289
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 886606..897442

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS38289_RS04440 (MGAS38289_01832)	-	887160..887528 (+)	369	WP_010922310.1	hypothetical protein	-
MGAS38289_RS04445 (MGAS38289_01834)	-	887578..888489 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
MGAS38289_RS04450 (MGAS38289_01836)	-	888606..889256 (-)	651	WP_002984629.1	hemolysin III family protein	-
MGAS38289_RS04455 (MGAS38289_01838)	-	889253..889693 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
MGAS38289_RS04460 (MGAS38289_01840)	ylqF	889912..890760 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
MGAS38289_RS04465 (MGAS38289_01842)	-	890750..891541 (+)	792	WP_011285534.1	ribonuclease HII	-
MGAS38289_RS04470 (MGAS38289_01844)	dprA	891606..892442 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
MGAS38289_RS04475 (MGAS38289_01846)	topA	892549..894678 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
MGAS38289_RS04480	-	894753..895635 (-)	883	Protein_845	LysR family transcriptional regulator	-
MGAS38289_RS04485 (MGAS38289_01850)	-	895648..896193 (+)	546	Protein_846	PTS sugar transporter subunit IIC	-
MGAS38289_RS04490 (MGAS38289_01852)	-	896208..897200 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=976926 MGAS38289_RS04470 WP_010922314.1 891606..892442(+) (dprA) [Streptococcus pyogenes strain MGAS38289]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=976926 MGAS38289_RS04470 WP_010922314.1 891606..892442(+) (dprA) [Streptococcus pyogenes strain MGAS38289]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367