Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   AAAF57_RS02370 Genome accession   NZ_CP150847
Coordinates   451722..452420 (+) Length   232 a.a.
NCBI ID   WP_410536889.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS5     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 446722..457420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAAF57_RS02345 (AAAF57_02345) - 447064..448650 (+) 1587 WP_410536887.1 DEAD/DEAH box helicase -
  AAAF57_RS02350 (AAAF57_02350) - 448706..448975 (-) 270 WP_022496129.1 GIY-YIG nuclease family protein -
  AAAF57_RS02355 (AAAF57_02355) - 448979..449743 (-) 765 WP_022496130.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  AAAF57_RS02360 (AAAF57_02360) - 449793..450728 (-) 936 WP_049545587.1 polysaccharide deacetylase family protein -
  AAAF57_RS02365 (AAAF57_02365) - 450858..451613 (+) 756 WP_022496132.1 lysophospholipid acyltransferase family protein -
  AAAF57_RS02370 (AAAF57_02370) comEA 451722..452420 (+) 699 WP_410536889.1 helix-hairpin-helix domain-containing protein Machinery gene
  AAAF57_RS02375 (AAAF57_02375) comEC/celB 452410..454650 (+) 2241 WP_349955294.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AAAF57_RS02380 (AAAF57_02380) - 454736..455998 (+) 1263 WP_084915391.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AAAF57_RS02385 (AAAF57_02385) - 456064..456609 (+) 546 WP_013991031.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 24490.39 Da        Isoelectric Point: 4.7321

>NTDB_id=972951 AAAF57_RS02370 WP_410536889.1 451722..452420(+) (comEA) [Streptococcus salivarius strain KSS5]
MKEKIIAYVKDNRLFVSVIALLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKDK
SKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSVNLAASLSDEEVVYVATKDENLSVLGQSGTQGQVSDK
GGQTSAKDGKINLNTATSEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLEKIRESLYVA

Nucleotide


Download         Length: 699 bp        

>NTDB_id=972951 AAAF57_RS02370 WP_410536889.1 451722..452420(+) (comEA) [Streptococcus salivarius strain KSS5]
GTGAAGGAAAAGATTATAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTTTACTGATGGTGATTTTTTG
CTTCTTTCTATGGATGACTTGTGGTGCGGGCAACAGTATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CCTCCTCATCCAAACAAAGCTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGGAAGTGAAAAGGATAAG
TCAAAAGTAACAGTAGATGTTAAGGGGGCTGTGGCTAATCCGGGTGTTTATACCTTAAAAGCAAGCGCTAGGGTAACTGA
TGCCATCAAAGCCGCTGGGGGAATGACTGAGGATGCGGATGCTAAGAGTGTTAACTTAGCTGCAAGCCTGTCGGACGAAG
AGGTTGTCTATGTGGCAACTAAGGATGAAAACCTTTCTGTTCTTGGTCAATCAGGAACTCAGGGTCAGGTTTCTGACAAA
GGAGGGCAAACTAGTGCTAAGGATGGCAAAATTAACTTAAACACAGCGACTTCAGAGGAGTTGCAAACTATTTCTGGGAT
TGGAGCTAAGCGTGCTGAGGATATCATTGCCTATCGTGAAAGTCATGGAGGTTTTCAATCCGTAGATGACTTGAAAAATG
TCTCAGGAATTGGTGATAAAACTTTAGAAAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(169-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

91.379

100

0.914
  comEA/celA/cilE Streptococcus mitis SK321

42.609

99.138

0.422
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

41.048

98.707

0.405
  comEA/celA/cilE Streptococcus pneumoniae Rx1

40.611

98.707

0.401
  comEA/celA/cilE Streptococcus pneumoniae D39

40.611

98.707

0.401
  comEA/celA/cilE Streptococcus pneumoniae R6

40.611

98.707

0.401
  comEA/celA/cilE Streptococcus mitis NCTC 12261

39.301

98.707

0.388

Multiple sequence alignment