Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   NYE79_RS09975 Genome accession   NZ_CP150168
Coordinates   2043756..2045075 (-) Length   439 a.a.
NCBI ID   WP_000362886.1    Uniprot ID   -
Organism   Streptococcus sp. FSL W8-0197     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2038756..2050075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS09950 (NYE79_09950) - 2039444..2042098 (-) 2655 WP_000472068.1 YhgE/Pip domain-containing protein -
  NYE79_RS09955 (NYE79_09955) - 2042227..2042769 (+) 543 WP_000665080.1 TetR-like C-terminal domain-containing protein -
  NYE79_RS09970 (NYE79_09970) comE 2043007..2043759 (-) 753 WP_000866079.1 competence system response regulator transcription factor ComE Regulator
  NYE79_RS09975 (NYE79_09975) comD 2043756..2045075 (-) 1320 WP_000362886.1 competence system sensor histidine kinase ComD Regulator
  NYE79_RS09980 (NYE79_09980) comC/comC2 2045096..2045221 (-) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  NYE79_RS09990 (NYE79_09990) rlmH 2045503..2045982 (-) 480 WP_000694219.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  NYE79_RS09995 (NYE79_09995) htrA 2046168..2047364 (+) 1197 WP_084877132.1 S1C family serine protease Regulator
  NYE79_RS10000 (NYE79_10000) spo0J 2047422..2048180 (+) 759 WP_216728672.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51241.29 Da        Isoelectric Point: 7.0077

>NTDB_id=964645 NYE79_RS09975 WP_000362886.1 2043756..2045075(-) (comD) [Streptococcus sp. FSL W8-0197]
MDLFGLGIAIFYFLIISKSYEWICKINRKEQIVFFCYTCISVFILEEIITLVFSNSFALSKFLFPLVVYLYLRKLKKSEK
YKAIFISLLLSLLYHSTHTFISVTLSSIIGDEVVLHYKSTFLLVVLLMTYFSILIIIRYFHLDIKYFDKDYLYPFLKKVI
VAFFGLHILLFISDIVSTTHHLNSFGSILSTIVFICLLLIFFAMNSHKVQIEKEIALKQKKFEQKHLQTYTDEIVELYNE
IRGFRHDYAGMLVSMQMAIDSGDLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIEDSALRSLIAQSIVYARKNDVEFTL
EVKDIITRLSIDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=964645 NYE79_RS09975 WP_000362886.1 2043756..2045075(-) (comD) [Streptococcus sp. FSL W8-0197]
ATGGATTTATTTGGATTAGGGATAGCTATTTTTTATTTTCTCATCATTAGCAAAAGTTATGAATGGATTTGTAAAATAAA
TAGAAAAGAACAAATTGTTTTTTTCTGTTACACATGTATCTCAGTTTTTATACTTGAAGAAATTATTACACTAGTATTTT
CTAATAGTTTTGCTTTGTCTAAATTTTTATTTCCTTTGGTTGTGTACCTTTATTTAAGAAAGTTAAAGAAGTCTGAAAAA
TACAAAGCTATTTTTATCAGTTTACTACTGTCTTTATTATATCACAGTACTCATACTTTTATATCCGTAACCTTATCTTC
TATAATAGGAGATGAAGTAGTATTACACTATAAAAGTACATTCCTTTTAGTAGTATTGTTAATGACTTATTTTTCTATTC
TAATAATAATCCGTTATTTTCATCTGGATATTAAATATTTTGATAAAGATTATCTGTACCCTTTTTTAAAAAAAGTAATA
GTTGCTTTCTTTGGTTTGCATATCTTATTGTTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTCACAAGGTTCAAATTGAAAAAG
AGATTGCTCTAAAACAAAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATTGTGGAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCAGGGATGCTTGTCAGCATGCAAATGGCGATTGACAGTGGAGATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTCTTAGTAAAAGCAAATCAGAAATTGAGGTCAGAAAAATATACTTACTTTGATTTAAATA
ATATAGAAGACTCTGCTTTACGAAGTTTAATTGCTCAATCGATTGTCTATGCACGAAAAAATGATGTAGAGTTTACATTG
GAAGTAAAGGATATCATTACTAGACTGTCAATAGATTTACTTGATCTTGTTCGTATCATGAGCATTTTATTAAACAATGC
TGTTGAAGGTGCTGCAGATAGTTACTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAAACAGTTATAGTTA
TCCAGAATTCATGCAAAATCACTATGACGCCTTCAGAGGATTTATTTGCCTTAGGTTTCTCTACCAAGGGAAGAAATAGA
GGTCTAGGACTTAATAATGTCAAGGAGATTTTAGATAAGTATGACAACATTATTTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

75.057

100

0.754
  comD Streptococcus mitis NCTC 12261

74.603

100

0.749
  comD/comD2 Streptococcus pneumoniae TIGR4

74.15

100

0.745
  comD/comD1 Streptococcus pneumoniae R6

73.696

100

0.74
  comD/comD1 Streptococcus pneumoniae Rx1

73.696

100

0.74
  comD/comD1 Streptococcus pneumoniae D39

73.696

100

0.74
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.465

85.194

0.421
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.936

85.649

0.419

Multiple sequence alignment