Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   NYE79_RS00220 Genome accession   NZ_CP150168
Coordinates   35784..37133 (+) Length   449 a.a.
NCBI ID   WP_070657245.1    Uniprot ID   -
Organism   Streptococcus sp. FSL W8-0197     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 30784..42133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS00175 (NYE79_00175) - 31346..31582 (+) 237 WP_000136435.1 acyl carrier protein -
  NYE79_RS00180 (NYE79_00180) - 31897..32040 (+) 144 WP_000180838.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  NYE79_RS00185 (NYE79_00185) - 32058..32207 (+) 150 WP_001052546.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  NYE79_RS00190 (NYE79_00190) - 32220..32396 (+) 177 WP_186822451.1 hypothetical protein -
  NYE79_RS00195 (NYE79_00195) - 32546..32701 (+) 156 WP_000661692.1 hypothetical protein -
  NYE79_RS00200 (NYE79_00200) - 32726..32947 (+) 222 WP_049478100.1 hypothetical protein -
  NYE79_RS00205 (NYE79_00205) - 32985..33173 (+) 189 WP_000722238.1 hypothetical protein -
  NYE79_RS00210 (NYE79_00210) - 33198..33407 (+) 210 WP_000869801.1 hypothetical protein -
  NYE79_RS00215 (NYE79_00215) comA 33618..35771 (+) 2154 WP_070657243.1 peptide cleavage/export ABC transporter ComA Regulator
  NYE79_RS00220 (NYE79_00220) comB 35784..37133 (+) 1350 WP_070657245.1 competence pheromone export protein ComB Regulator
  NYE79_RS00225 (NYE79_00225) purC 37302..38009 (+) 708 WP_070657248.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  NYE79_RS00230 (NYE79_00230) - 38066..41791 (+) 3726 WP_070657251.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49882.82 Da        Isoelectric Point: 5.3839

>NTDB_id=964577 NYE79_RS00220 WP_070657245.1 35784..37133(+) (comB) [Streptococcus sp. FSL W8-0197]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLMFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVGNYLEENKL
VKQGDLLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNAAYSFYQTYKNQGEENPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAHATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEQ
GNFFKIEAETHLTSEQAATLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=964577 NYE79_RS00220 WP_070657245.1 35784..37133(+) (comB) [Streptococcus sp. FSL W8-0197]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGCTCATGTTTTTACTGGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTATCTACCAGAGCAACTGTCG
AACCTAGTCGGATCATTGCCAACATCCAGTCGACTAGCAATCAACGCATTGTGGGCAACTATCTGGAAGAAAACAAGTTG
GTCAAGCAAGGAGATCTGCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTTGAGGCATATGCCAGTCAATTGGA
GATGCTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTCCCAGAGGCGG
ATAAGTTTGGTTATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGGAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCTTCTCAAAATGCGGCAGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGTCAAACAGAGGATAA
AATTCGAGACTACAAAACAGCAAAGTCAGCGATTGAAAAGGGAGATCAACTGGATAGTCAAAATGCAGCCTACTCTTTTT
ACCAGACCTATAAAAACCAAGGTGAAGAAAATCCGCAAGCTAAATCGCAAGTTATTGCGCAAGTGGATGCTCAAATTGCC
CAGCTAGAGTCTAGTCTAGCTACGTATCGTGTACAGTATGCGGGTTCTGGAGCTCAGCAGGCCCACGCAACGGGATTGGA
TAGTCAACTGGAATCGCTCAAGTCTCAGCACTTAGTCAAAGTTGGCCAGGAATTAACTCTTCTAGATCAGAAAATTTTGG
AGGCGGAATCGGGTAAGAAGGTACAGGGAGGTCTCCTAGATAAAGGGAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAAACCAGTGATTCTACCATGGTCGCAGAAGGAACCCTGCTAGCCCAACTCTATCCATCCCTGGAAAAAGA
AGGGAAAACTAAACTCACAGCCTATCTCAGTTCAAAGGATGTTGCTAGAGTCAAGATTGGGGACTCTGTCCGTTATACTA
CGACTAATGATGCCAAGAATCAAATTTTCCTGGATTCTACGATTACAAGTATTGATGCGACAGCTACAAAGACTGAACAA
GGAAATTTCTTTAAAATTGAGGCGGAGACCCATCTGACTTCTGAGCAGGCTGCAACACTTCGCTATGGTTTAGAAGGCCG
CCTGCAGATGATTACGGGAAAGAAAAGCTATCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

83.929

99.777

0.837
  comB Streptococcus pneumoniae Rx1

83.036

99.777

0.829
  comB Streptococcus pneumoniae D39

83.036

99.777

0.829
  comB Streptococcus pneumoniae R6

83.036

99.777

0.829
  comB Streptococcus pneumoniae TIGR4

82.589

99.777

0.824
  comB Streptococcus mitis NCTC 12261

82.589

99.777

0.824
  comB Streptococcus gordonii str. Challis substr. CH1

54.646

100

0.55

Multiple sequence alignment