Detailed information NTG0964576

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: NYE79_RS00215
• Genome accession: NZ_CP150168
• Coordinates: 33618..35771 (+)
• Length: 717 a.a.
• NCBI ID: WP_070657243.1
• Uniprot ID: -
• Organism: Streptococcus sp. FSL W8-0197
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 28618..40771

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NYE79_RS00165 (NYE79_00165)	recO	29581..30351 (+)	771	WP_045593786.1	DNA repair protein RecO	-
NYE79_RS00170 (NYE79_00170)	plsX	30348..31340 (+)	993	WP_070657240.1	phosphate acyltransferase PlsX	-
NYE79_RS00175 (NYE79_00175)	-	31346..31582 (+)	237	WP_000136435.1	acyl carrier protein	-
NYE79_RS00180 (NYE79_00180)	-	31897..32040 (+)	144	WP_000180838.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
NYE79_RS00185 (NYE79_00185)	-	32058..32207 (+)	150	WP_001052546.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
NYE79_RS00190 (NYE79_00190)	-	32220..32396 (+)	177	WP_186822451.1	hypothetical protein	-
NYE79_RS00195 (NYE79_00195)	-	32546..32701 (+)	156	WP_000661692.1	hypothetical protein	-
NYE79_RS00200 (NYE79_00200)	-	32726..32947 (+)	222	WP_049478100.1	hypothetical protein	-
NYE79_RS00205 (NYE79_00205)	-	32985..33173 (+)	189	WP_000722238.1	hypothetical protein	-
NYE79_RS00210 (NYE79_00210)	-	33198..33407 (+)	210	WP_000869801.1	hypothetical protein	-
NYE79_RS00215 (NYE79_00215)	comA	33618..35771 (+)	2154	WP_070657243.1	peptide cleavage/export ABC transporter ComA	Regulator
NYE79_RS00220 (NYE79_00220)	comB	35784..37133 (+)	1350	WP_070657245.1	competence pheromone export protein ComB	Regulator
NYE79_RS00225 (NYE79_00225)	purC	37302..38009 (+)	708	WP_070657248.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80540.91 Da
• Isoelectric Point: 7.3721

>NTDB_id=964576 NYE79_RS00215 WP_070657243.1 33618..35771(+) (comA) [Streptococcus sp. FSL W8-0197]
MKFRKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVIGQDKKHIHIADPDPSIKLTKISRERFAQEWTGVSIFMAPSPDYKPHKEKKQGLLSFLPI
LLKQRGLITNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
KGDMTFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKSLRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLNKGKIVEEGTHADLLAQDGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=964576 NYE79_RS00215 WP_070657243.1 33618..35771(+) (comA) [Streptococcus sp. FSL W8-0197]
ATGAAATTTAGGAAAAGGCACTATCGTCCTCAGGTGGACCAGATGGATTGTGGCGTGGCTTCCTTGGCTATGGTCTTTGG
TTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAGTTGGCAAAGACGACCATGGATGGGACGACCGCTTTGGGAC
TTGTAAAGGTGGCAGAGGAGATTGGATTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATTTGCCAGATTTG
ACCTTTCCTTTTGTGGCTCATGTGCTCAAGGAAGGGAAGTTGCTCCACTACTATGTGGTGATAGGTCAGGATAAAAAGCA
CATTCATATCGCTGATCCAGATCCTAGTATCAAGCTGACCAAGATTTCCCGTGAGCGATTTGCGCAAGAGTGGACAGGGG
TTAGTATTTTTATGGCACCATCACCGGACTATAAACCTCATAAGGAGAAAAAACAGGGACTCCTATCCTTCTTGCCGATC
TTACTCAAGCAGCGTGGCTTAATTACCAATATCGTCCTAGCGACACTCTTGGTGACCTTGATCAATATCGTGGGTTCCTA
CTATCTTCAGTCCATCATTGATAGTTACGTACCAGACCAGATGCGTTCGACCTTGGGCATTATCTCAATAGGACTAGTCA
TCGTCTATATTCTCCAGCAAATTTTGTCTTATGCCCAGGAATATCTTCTACTAATCCTTGGGCAACGCTTGTCGATTGAC
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCGATGTCCTTTTTTGCGACACGCAGGACAGGAGAAATCGTTTC
TCGTTTTACAGATGCCAATAGTATCATCGATGCGCTAGCTTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTTGTCTTGTTTTCACAAAATATGACGCTCTTTTTCATTAGTCTACTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCTTTTATGAAGCCGTTTGAAAAGATGAATCGAGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAATGGTATTGAGACCATTAAGTCTTTGACCAGTGAAAGTTCGCGCTATCAAAAGATTGACAAGGAAT
TTGTGGCTTATCTGAAAAAATCTTTTACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCGCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGCTGGGAGCTATTCTTGTCATGGATGGGAAAATGAGTTTGGGCCAGCTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATCAACCTACAAACCAAACTTCAGACAGCTCAGGTCG
CCAATAACCGTCTTAACGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTAGAAGATTTGAGCATGATG
AAAGGGGATATGACCTTTAAACAAGTTCACTATAAGTATGGCTATGGGCGTGATGTCTTGTCGGATATCAATTTGACCAT
TCCGCAAGGGTCTAAGATGGCTTTTGTGGGGATTTCGGGATCCGGTAAGACGACTTTGGCCAAGATGATGGTTAATTTCT
ACGATCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAATCCTTGCGCCAGTACATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCTAAGGAGGGGACGAC
TCAGGAAGATATCTTACGAGCAGTCGAGTTGGCAGAGATTCGGGAGGATATTGAGCGCATGCCACTGAATTACCAGACAG
AATTAACTTCGGATGGGGCTGGAATTTCTGGTGGGCAACGGCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACGGATGCA
CCTGTCTTGATCTTGGACGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTCGATAATCTCATGGCTTT
AGACAAGACCTTGATTTTCATCGCCCATCGTTTGACCATCGCTGAGCGAACAGAAAAGGTTGTTGTTCTGAATAAGGGCA
AGATTGTTGAAGAGGGTACCCATGCAGACTTGCTTGCACAGGATGGCTTTTACGCCCATTTGGTAAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	94.282	100	0.943
comA	Streptococcus pneumoniae Rx1	94.003	100	0.94
comA	Streptococcus pneumoniae D39	94.003	100	0.94
comA	Streptococcus pneumoniae R6	94.003	100	0.94
comA	Streptococcus mitis SK321	94.003	100	0.94
comA	Streptococcus pneumoniae TIGR4	93.584	100	0.936
comA	Streptococcus gordonii str. Challis substr. CH1	80.195	100	0.802
comA/nlmT	Streptococcus mutans UA159	64.296	100	0.643