Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   AABA19_RS10110 Genome accession   NZ_AP028609
Coordinates   1955870..1956274 (-) Length   134 a.a.
NCBI ID   WP_223842268.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep4     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1950870..1961274
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS10080 (TKY121806_19510) - 1951179..1952054 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  AABA19_RS10085 (TKY121806_19520) pstC 1952172..1953035 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  AABA19_RS10090 (TKY121806_19530) pstA 1953028..1953843 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  AABA19_RS10095 (TKY121806_19540) pstB 1953845..1954597 (+) 753 WP_000536447.1 phosphate ABC transporter ATP-binding protein PstB -
  AABA19_RS10100 (TKY121806_19550) phoU 1954612..1955262 (+) 651 WP_338170790.1 phosphate signaling complex protein PhoU -
  AABA19_RS10105 (TKY121806_19560) - 1955303..1955755 (+) 453 Protein_1952 transposase -
  AABA19_RS10110 (TKY121806_19570) comR 1955870..1956274 (-) 405 WP_223842268.1 helix-turn-helix domain-containing protein Regulator
  AABA19_RS10115 (TKY121806_19580) - 1956522..1957538 (+) 1017 WP_000415110.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  AABA19_RS10120 (TKY121806_19590) galU 1957560..1958459 (+) 900 WP_000202228.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  AABA19_RS10125 (TKY121806_19600) - 1958526..1959203 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  AABA19_RS10130 (TKY121806_19610) - 1959187..1959726 (-) 540 WP_338170795.1 5-formyltetrahydrofolate cyclo-ligase -
  AABA19_RS10135 (TKY121806_19620) - 1959738..1960868 (-) 1131 WP_338170798.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 16261.66 Da        Isoelectric Point: 4.5242

>NTDB_id=96017 AABA19_RS10110 WP_223842268.1 1955870..1956274(-) (comR) [Streptococcus pneumoniae strain Sep4]
MAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETI
TQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 405 bp        

>NTDB_id=96017 AABA19_RS10110 WP_223842268.1 1955870..1956274(-) (comR) [Streptococcus pneumoniae strain Sep4]
TTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAA
TGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAA
GTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATC
ACCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCAT
CCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCT
GGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(60-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.63

80.597

0.44
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

54.717

79.104

0.433
  comR Streptococcus pyogenes MGAS315

52.778

80.597

0.425
  comR Streptococcus mutans UA159

50

80.597

0.403
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

48.039

76.119

0.366
  comR Streptococcus suis P1/7

46.226

79.104

0.366
  comR Streptococcus suis 05ZYH33

46.226

79.104

0.366

Multiple sequence alignment