Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   QMM10_RS09565 Genome accession   NZ_AP025938
Coordinates   1875782..1876798 (-) Length   338 a.a.
NCBI ID   WP_078133850.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701057     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1870782..1881798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM10_RS09520 - 1870866..1870997 (-) 132 WP_000768904.1 hypothetical protein -
  QMM10_RS09525 (PC1044_18510) - 1870998..1872188 (-) 1191 WP_000167766.1 acetate kinase -
  QMM10_RS09530 (PC1044_18520) comYH 1872239..1873192 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  QMM10_RS09535 (PC1044_18530) - 1873253..1873840 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  QMM10_RS09540 (PC1044_18540) comGG/cglG 1873977..1874390 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  QMM10_RS09545 comGF/cglF 1874368..1874829 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  QMM10_RS09550 (PC1044_18560) comGE/cglE 1874792..1875094 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  QMM10_RS09555 (PC1044_18570) comGD/cglD 1875057..1875461 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  QMM10_RS09560 (PC1044_18580) comGC/cglC 1875454..1875780 (-) 327 WP_000738638.1 comG operon protein ComGC Machinery gene
  QMM10_RS09565 (PC1044_18590) comGB/cglB 1875782..1876798 (-) 1017 WP_078133850.1 competence type IV pilus assembly protein ComGB Machinery gene
  QMM10_RS09570 (PC1044_18600) comGA/cglA/cilD 1876746..1877687 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  QMM10_RS09575 (PC1044_18610) - 1877763..1878128 (-) 366 WP_000286415.1 DUF1033 family protein -
  QMM10_RS09580 (PC1044_18620) - 1878279..1879337 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  QMM10_RS09585 (PC1044_18630) nagA 1879500..1880651 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38552.66 Da        Isoelectric Point: 9.7316

>NTDB_id=95391 QMM10_RS09565 WP_078133850.1 1875782..1876798(-) (comGB/cglB) [Streptococcus pneumoniae strain PZ900701057]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVRTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=95391 QMM10_RS09565 WP_078133850.1 1875782..1876798(-) (comGB/cglB) [Streptococcus pneumoniae strain PZ900701057]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTCCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAGTATCTAGACAATCT
GGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGTTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCGGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCGTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae D39

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae R6

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae TIGR4

98.817

100

0.988
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

94.083

100

0.941
  comYB Streptococcus gordonii str. Challis substr. CH1

71.131

99.408

0.707
  comYB Streptococcus mutans UA140

57.862

94.083

0.544
  comYB Streptococcus mutans UA159

57.862

94.083

0.544
  comGB Lactococcus lactis subsp. cremoris KW2

51.198

98.817

0.506

Multiple sequence alignment