Detailed information NTG0095199

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: AAA985_RS00680
• Genome accession: NZ_AP028603
• Coordinates: 109734..111887 (+)
• Length: 717 a.a.
• NCBI ID: WP_000668282.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Pne2
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 104734..116887

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA985_RS00645 (TKY181970_01250)	-	105154..106323 (+)	1170	WP_000366342.1	pyridoxal phosphate-dependent aminotransferase	-
AAA985_RS00650 (TKY181970_01260)	recO	106320..107090 (+)	771	WP_000616164.1	DNA repair protein RecO	Machinery gene
AAA985_RS00655 (TKY181970_01270)	plsX	107087..108079 (+)	993	WP_000717467.1	phosphate acyltransferase PlsX	-
AAA985_RS00660 (TKY181970_01280)	-	108085..108318 (+)	234	WP_000136447.1	acyl carrier protein	-
AAA985_RS00665 (TKY181970_01290)	-	108364..108654 (+)	291	Protein_125	IS5/IS1182 family transposase	-
AAA985_RS00670 (TKY181970_01300)	cipB	108857..109015 (+)	159	WP_001093073.1	bacteriocin class II family protein	Regulator
AAA985_RS00675	-	109018..109143 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
AAA985_RS00680 (TKY181970_01310)	comA	109734..111887 (+)	2154	WP_000668282.1	peptide cleavage/export ABC transporter ComA	Regulator
AAA985_RS00685 (TKY181970_01320)	comB	111900..113249 (+)	1350	WP_000801620.1	competence pheromone export protein ComB	Regulator
AAA985_RS00690 (TKY181970_01330)	purC	113419..114126 (+)	708	WP_000043300.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
AAA985_RS00695	-	114137..114271 (+)	135	WP_000429437.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80354.38 Da
• Isoelectric Point: 6.3368

>NTDB_id=95199 AAA985_RS00680 WP_000668282.1 109734..111887(+) (comA) [Streptococcus pneumoniae strain Pne2]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAALSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGEMTFKQVHYKYGYGRDVLSDINLTVPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=95199 AAA985_RS00680 WP_000668282.1 109734..111887(+) (comA) [Streptococcus pneumoniae strain Pne2]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAAGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGTTATTATTTTTTGGCTCACTTGCGAGAATTGGCTAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATTGGCTTTGAGACACGAGCTATCAAGGCGGATATGACGCTTTTTGATTTGCCCGATTTG
ACTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGACAG
CATTCATATTGCCGATCCAGATCCTGGGGTGAAATTGACCAAACTGCCACGTGAGCGTTTTGAGGAAGAATGGACAGGAG
TGACTCTGTTTATGGCACCTAGTCCAGACTACAAGCCTCATAAGGATCAAAAGAATGGTCTGCTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAATATCGTTTTGGCAACACTCTTGGTAACCTTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGTTGGGGATTATTTCTATTGGGCTAGTCA
TCGTCTACATCCTCCAGCAAATCTTGTCTTACGCTCAGGAGTATCTCTTGCTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTGATTTTGTCCTATATCAAGCATGTTTTTCACCTCCCTATGTCCTTCTTTGCGACACGCAGGACAGGGGAGATCGTGTC
TCGTTTTACAGATGCTAACAGTATCATCGATGCGCTGGCTTCGACCATCCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCCCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCGCTTCCTATCTACACAGTG
ATTATCTTTGCCTTTATGAAGCCATTTGAAAAGATGAATCGGGACACCATGGAAGCCAATGCGGCTCTGTCTTCTTCTAT
CATTGAGGACATCAATGGTATTGAGACTATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAAATTGACAAGGAAT
TTGTGGATTATCTGAAGAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAGGTTGCCCATCTC
TTGCTTAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAAGTGTATCTAGTAGCTTCTGAGTTTGAGGAGAAGAAAACAGTTGAGGATTTGAGCTTGATG
AAGGGAGAGATGACTTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGACGTCTTGTCGGATATCAATTTAACCGT
TCCCCAAGGGTCTAAGGTGGCTTTTGTGGGGATTTCAGGGTCAGGTAAGACGACTTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAAGGGGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTGCGCCAGTACATC
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCCAAGGAGGGGACGAC
ACAGGAAGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGAGAGGATATCGAGCGCATGCCACTGAATTATCAGACAG
AATTGACTTCGGATGGGGCAGGGATTTCAGGTGGTCAACGTCAGAGAATCGCTTTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTCGATAATCTCATGGCTTT
GGACAAGACCTTGATTTTCATTGCTCACCGCTTGACTATTGCTGAGCGGACAGAGAAGGTAGTTGTCTTGGATCAGGGCA
AGATTGTCGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGGTGGCTTTTACGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae Rx1	99.303	100	0.993
comA	Streptococcus pneumoniae D39	99.303	100	0.993
comA	Streptococcus pneumoniae R6	99.303	100	0.993
comA	Streptococcus pneumoniae TIGR4	98.884	100	0.989
comA	Streptococcus mitis SK321	98.605	100	0.986
comA	Streptococcus mitis NCTC 12261	98.605	100	0.986
comA	Streptococcus gordonii str. Challis substr. CH1	80.614	100	0.806
comA/nlmT	Streptococcus mutans UA159	64.714	100	0.647