Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   QML87_RS04605 Genome accession   NZ_AP025936
Coordinates   918997..919701 (+) Length   234 a.a.
NCBI ID   WP_000722076.1    Uniprot ID   Q9S1K0
Organism   Streptococcus pneumoniae strain PZ900700617     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 913997..924701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML87_RS04585 (PC0607_09070) coaC 914286..914837 (-) 552 WP_001284128.1 phosphopantothenoylcysteine decarboxylase -
  QML87_RS04590 (PC0607_09080) coaB 914849..915538 (-) 690 WP_000699488.1 phosphopantothenate--cysteine ligase -
  QML87_RS04595 (PC0607_09090) - 915768..917438 (+) 1671 WP_000845290.1 formate--tetrahydrofolate ligase -
  QML87_RS04600 (PC0607_09100) mutY 917767..918942 (+) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  QML87_RS04605 (PC0607_09110) micA 918997..919701 (+) 705 WP_000722076.1 response regulator YycF Regulator
  QML87_RS04610 (PC0607_09120) micB 919694..921043 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  QML87_RS04615 (PC0607_09130) vicX 921045..921854 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  QML87_RS04620 (PC0607_09140) - 921945..922187 (+) 243 WP_000208080.1 DUF6290 family protein -
  QML87_RS04625 (PC0607_09150) - 922189..922443 (+) 255 WP_001812387.1 type II toxin-antitoxin system RelE/ParE family toxin -
  QML87_RS04630 (PC0607_09160) - 922490..923264 (+) 775 Protein_920 ion channel -
  QML87_RS04635 (PC0607_09170) - 923527..924513 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26815.63 Da        Isoelectric Point: 4.7164

>NTDB_id=95196 QML87_RS04605 WP_000722076.1 918997..919701(+) (micA) [Streptococcus pneumoniae strain PZ900700617]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=95196 QML87_RS04605 WP_000722076.1 918997..919701(+) (micA) [Streptococcus pneumoniae strain PZ900700617]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACAAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 1NXS
  PDB 2A9O
  PDB 2A9P

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

100

100

1
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.197

99.573

0.38

Multiple sequence alignment