Detailed information NTG0949976

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: WGK59_RS03130
• Genome accession: NZ_CP148002
• Coordinates: 615833..617170 (+)
• Length: 445 a.a.
• NCBI ID: WP_015701646.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain AR2427
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 610833..622170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WGK59_RS03105 (WGK59_03105)	-	610898..613492 (-)	2595	WP_015701649.1	penicillin-binding protein 1A	-
WGK59_RS03110 (WGK59_03110)	comA	613591..614388 (+)	798	WP_005693722.1	competence protein A	Machinery gene
WGK59_RS03115 (WGK59_03115)	comB	614389..614895 (+)	507	WP_011272049.1	competence protein ComB	Machinery gene
WGK59_RS03120 (WGK59_03120)	comC	614892..615413 (+)	522	WP_015701648.1	competence protein ComC	Machinery gene
WGK59_RS03125 (WGK59_03125)	comD	615410..615823 (+)	414	WP_015701647.1	pilus assembly protein PilP	Machinery gene
WGK59_RS03130 (WGK59_03130)	comE	615833..617170 (+)	1338	WP_015701646.1	type IV pilus secretin PilQ family protein	Machinery gene
WGK59_RS03135 (WGK59_03135)	-	617183..617869 (+)	687	WP_015701645.1	ComF family protein	-
WGK59_RS03140 (WGK59_03140)	nfuA	617945..618541 (+)	597	WP_005649300.1	Fe-S biogenesis protein NfuA	-
WGK59_RS03145 (WGK59_03145)	nudC	618608..619402 (+)	795	WP_015701644.1	NAD(+) diphosphatase	-
WGK59_RS03150 (WGK59_03150)	-	619438..620028 (+)	591	WP_015701643.1	YjaG family protein	-
WGK59_RS03155 (WGK59_03155)	-	620168..620440 (+)	273	WP_005630954.1	HU family DNA-binding protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49207.47 Da
• Isoelectric Point: 7.8816

>NTDB_id=949976 WGK59_RS03130 WP_015701646.1 615833..617170(+) (comE) [Haemophilus influenzae strain AR2427]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQHDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPDGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PIIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide

• Length: 1338 bp

>NTDB_id=949976 WGK59_RS03130 WP_015701646.1 615833..617170(+) (comE) [Haemophilus influenzae strain AR2427]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTAGAGCAATTAGCTTTTCAACATGATG
TCAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGAGTTTATTATTTAAACGGCAGCCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCACACTTAGTGAGTCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCCGATGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTTGCCAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCGGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCATTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (269-429)

• Bacterial type II/III secretion system short domain (Secretin_N) (123-187)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae 86-028NP	98.652	100	0.987
comE	Haemophilus influenzae Rd KW20	97.528	100	0.975
comE	Glaesserella parasuis strain SC1401	52	95.506	0.497
pilQ	Vibrio campbellii strain DS40M4	42.959	94.157	0.404
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	41.99	92.584	0.389
pilQ	Vibrio cholerae strain A1552	41.99	92.584	0.389