Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   WGK59_RS03115 Genome accession   NZ_CP148002
Coordinates   614389..614895 (+) Length   168 a.a.
NCBI ID   WP_011272049.1    Uniprot ID   Q4QNA7
Organism   Haemophilus influenzae strain AR2427     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 609389..619895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WGK59_RS03095 (WGK59_03095) - 609494..609823 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  WGK59_RS03100 (WGK59_03100) - 609976..610821 (-) 846 WP_015701650.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  WGK59_RS03105 (WGK59_03105) - 610898..613492 (-) 2595 WP_015701649.1 penicillin-binding protein 1A -
  WGK59_RS03110 (WGK59_03110) comA 613591..614388 (+) 798 WP_005693722.1 competence protein A Machinery gene
  WGK59_RS03115 (WGK59_03115) comB 614389..614895 (+) 507 WP_011272049.1 competence protein ComB Machinery gene
  WGK59_RS03120 (WGK59_03120) comC 614892..615413 (+) 522 WP_015701648.1 competence protein ComC Machinery gene
  WGK59_RS03125 (WGK59_03125) comD 615410..615823 (+) 414 WP_015701647.1 pilus assembly protein PilP Machinery gene
  WGK59_RS03130 (WGK59_03130) comE 615833..617170 (+) 1338 WP_015701646.1 type IV pilus secretin PilQ family protein Machinery gene
  WGK59_RS03135 (WGK59_03135) - 617183..617869 (+) 687 WP_015701645.1 ComF family protein -
  WGK59_RS03140 (WGK59_03140) nfuA 617945..618541 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  WGK59_RS03145 (WGK59_03145) nudC 618608..619402 (+) 795 WP_015701644.1 NAD(+) diphosphatase -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19697.54 Da        Isoelectric Point: 7.4684

>NTDB_id=949973 WGK59_RS03115 WP_011272049.1 614389..614895(+) (comB) [Haemophilus influenzae strain AR2427]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQTSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=949973 WGK59_RS03115 WP_011272049.1 614389..614895(+) (comB) [Haemophilus influenzae strain AR2427]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAAGCGCAGCAAA
CATCTTTTGAACAACTTAATCAGCAACTTCACAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGCTTGGAAGGTAACGCACAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

100

100

1
  comB Haemophilus influenzae Rd KW20

98.81

100

0.988