Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   V6K67_RS01610 Genome accession   NZ_CP145941
Coordinates   307448..308683 (+) Length   411 a.a.
NCBI ID   WP_338500873.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TCI633     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 302448..313683
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6K67_RS01580 (V6K67_01580) - 302914..305520 (+) 2607 WP_011226710.1 YfhO family protein -
  V6K67_RS01600 (V6K67_01600) - 306065..306748 (-) 684 WP_011226711.1 YoaK family protein -
  V6K67_RS01605 (V6K67_01605) rlmH 306764..307243 (-) 480 WP_011226712.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  V6K67_RS01610 (V6K67_01610) htrA 307448..308683 (+) 1236 WP_338500873.1 trypsin-like peptidase domain-containing protein Regulator
  V6K67_RS01615 (V6K67_01615) spo0J 308749..309516 (+) 768 WP_011226714.1 ParB/RepB/Spo0J family partition protein Regulator
  V6K67_RS01620 (V6K67_01620) dnaA 309756..311120 (+) 1365 WP_002948584.1 chromosomal replication initiator protein DnaA -
  V6K67_RS01625 (V6K67_01625) dnaN 311275..312411 (+) 1137 WP_011226715.1 DNA polymerase III subunit beta -
  V6K67_RS01630 (V6K67_01630) - 312462..312653 (+) 192 WP_011226716.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 42849.10 Da        Isoelectric Point: 4.7061

>NTDB_id=941231 V6K67_RS01610 WP_338500873.1 307448..308683(+) (htrA) [Streptococcus thermophilus strain TCI633]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINSGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=941231 V6K67_RS01610 WP_338500873.1 307448..308683(+) (htrA) [Streptococcus thermophilus strain TCI633]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCATGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACTCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGAATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(4-406)

PDZ domain (PDZ_2)

(307-402)

Trypsin-like peptidase domain (Trypsin_2)

(118-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.538

98.054

0.603
  htrA Streptococcus gordonii str. Challis substr. CH1

57.039

100

0.572
  htrA Streptococcus mitis NCTC 12261

53.545

99.513

0.533
  htrA Streptococcus pneumoniae TIGR4

53.301

99.513

0.53
  htrA Streptococcus pneumoniae D39

53.301

99.513

0.53
  htrA Streptococcus pneumoniae Rx1

53.301

99.513

0.53
  htrA Streptococcus pneumoniae R6

53.301

99.513

0.53