Detailed information NTG0941229

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: V6K67_RS00880
• Genome accession: NZ_CP145941
• Coordinates: 171538..172638 (-)
• Length: 366 a.a.
• NCBI ID: WP_148148900.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TCI633
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 166538..177638

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6K67_RS00840 (V6K67_00840)	-	167150..167347 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
V6K67_RS00845 (V6K67_00845)	-	167596..168789 (-)	1194	WP_338500846.1	acetate kinase	-
V6K67_RS00850 (V6K67_00850)	comYH	168845..169801 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
V6K67_RS00855 (V6K67_00855)	comGG	169846..170163 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
V6K67_RS00860 (V6K67_00860)	comYF	170141..170578 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
V6K67_RS00865 (V6K67_00865)	comGE	170562..170855 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
V6K67_RS00870 (V6K67_00870)	comYD	170827..171255 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
V6K67_RS00875 (V6K67_00875)	comYC	171215..171541 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
V6K67_RS00880 (V6K67_00880)	comYB	171538..172638 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
V6K67_RS00885 (V6K67_00885)	comGA/cglA/cilD	172520..173461 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
V6K67_RS00890 (V6K67_00890)	-	173542..173904 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41754.88 Da
• Isoelectric Point: 10.0449

>NTDB_id=941229 V6K67_RS00880 WP_148148900.1 171538..172638(-) (comYB) [Streptococcus thermophilus strain TCI633]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=941229 V6K67_RS00880 WP_148148900.1 171538..172638(-) (comYB) [Streptococcus thermophilus strain TCI633]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.394	90.164	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413