Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   V6U68_RS01360 Genome accession   NZ_CP145866
Coordinates   252496..254592 (+) Length   698 a.a.
NCBI ID   WP_247924952.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS9     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 247496..259592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS01335 (V6U68_01330) trkA 247586..248935 (-) 1350 WP_037598979.1 Trk system potassium transporter TrkA -
  V6U68_RS01340 (V6U68_01335) - 249213..249722 (+) 510 WP_021143543.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  V6U68_RS01345 (V6U68_01340) - 250033..250590 (+) 558 WP_002886542.1 ECF transporter S component -
  V6U68_RS01350 (V6U68_01345) - 250593..251243 (+) 651 WP_002889918.1 phosphatase PAP2 family protein -
  V6U68_RS01355 (V6U68_01350) comR 251422..252321 (+) 900 WP_049545716.1 helix-turn-helix transcriptional regulator Regulator
  V6U68_RS01360 (V6U68_01355) comA 252496..254592 (+) 2097 WP_247924952.1 peptide cleavage/export ABC transporter Regulator
  V6U68_RS01365 (V6U68_01360) - 254703..255035 (+) 333 WP_002886546.1 DUF805 domain-containing protein -
  V6U68_RS01370 (V6U68_01365) - 255087..256481 (-) 1395 WP_410531762.1 DUF4153 domain-containing protein -
  V6U68_RS01375 (V6U68_01370) - 256886..257401 (+) 516 WP_002886548.1 AmiS/UreI family transporter -
  V6U68_RS01380 (V6U68_01375) - 257426..257728 (+) 303 WP_002886558.1 urease subunit gamma -
  V6U68_RS01385 (V6U68_01380) - 257740..258051 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78553.58 Da        Isoelectric Point: 9.1895

>NTDB_id=940695 V6U68_RS01360 WP_247924952.1 252496..254592(+) (comA) [Streptococcus salivarius strain KSS9]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIVHVVKEGGLQHYYTVFGQIKEQLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGEAYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQAIIDRLIPQGAYNLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIIQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYREIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAF
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLIKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNLFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=940695 V6U68_RS01360 WP_247924952.1 252496..254592(+) (comA) [Streptococcus salivarius strain KSS9]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGAGAGTTGGCTCAGACTTCTCGTGAAGGTACTTCTGCGCTTGGTTTGGTGG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGTACATGTGGTTAAAGAAGGTGGGCTGCAGCATTATTATACGGTGTTTGGTCAAATCAAGGAGCAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAATTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAGCCTATACTAAATACAAAGAAGATGTACCTGGACTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTATTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAAGCTATTATCGACCGCTTGATTCCTCAGGGGGCCTATAATCTTCTGACCATGATTTCGCTAGGCTTATGTATCTCTT
ATCTTGCTCAACAAGTTTTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGTAATTACCTGTCCATTGCTGTCATT
CTTCCTTATATCAAGCATGTCCTTTCCTTACCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGAGATGCTAACACCATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTATACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTTCCTCTTTATGTTTTAATCATT
CTGGCATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGTATTGAAACCTTAAAATCCTTGAGGGTTGAGGAAAGACGCTATCGGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCCTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGGTTAAAGACAGGGGTTCAGTTAGTTTCT
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATCATCAATCTCCAATCTAAAATTCAGCAAGCCAAAGTCGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTTTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACTCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGAAAAACGACCTTAGCTAAAATGTTGTCAGGTTATTATACGAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTAGCCATGCGGAGTTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACGGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTTATTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGCTTTCAGACCCAAGTATCTGAAGACGGTGGTTTGTCTG
GCGGTCAAAAACAAAGATTAGCTATAGCAAGGGCTCTATTGTCCAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGTAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTACGTCAACATGTCAGTCGTGTAGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
TATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter (ABC_tran)

(494-640)

ABC transporter transmembrane region (ABC_membrane)

(167-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

52.782

100

0.53
  comA Streptococcus gordonii str. Challis substr. CH1

52.874

99.713

0.527
  comA Streptococcus mitis NCTC 12261

52.496

100

0.527
  comA Streptococcus pneumoniae Rx1

52.354

100

0.526
  comA Streptococcus pneumoniae D39

52.354

100

0.526
  comA Streptococcus pneumoniae R6

52.354

100

0.526
  comA Streptococcus pneumoniae TIGR4

52.211

100

0.524
  comA/nlmT Streptococcus mutans UA159

50.725

98.854

0.501