Detailed information NTG0940682

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: V6U67_RS09970
• Genome accession: NZ_CP145865
• Coordinates: 2126052..2127287 (+)
• Length: 411 a.a.
• NCBI ID: WP_037611167.1
• Uniprot ID: A0AB33ZFB7
• Organism: Streptococcus salivarius strain KSS8
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2121052..2132287

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U67_RS09940 (V6U67_09940)	-	2121525..2124119 (+)	2595	WP_037611165.1	YfhO family protein	-
V6U67_RS09960 (V6U67_09960)	-	2124668..2125351 (-)	684	WP_002883977.1	YoaK family protein	-
V6U67_RS09965 (V6U67_09965)	rlmH	2125367..2125846 (-)	480	WP_022495861.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
V6U67_RS09970 (V6U67_09970)	htrA	2126052..2127287 (+)	1236	WP_037611167.1	S1C family serine protease	Regulator
V6U67_RS09975 (V6U67_09975)	spo0J	2127353..2128120 (+)	768	WP_013991348.1	ParB/RepB/Spo0J family partition protein	Regulator
V6U67_RS09980 (V6U67_09980)	dnaA	2128359..2129723 (+)	1365	WP_037611169.1	chromosomal replication initiator protein DnaA	-

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42958.12 Da
• Isoelectric Point: 4.6266

>NTDB_id=940682 V6U67_RS09970 WP_037611167.1 2126052..2127287(+) (htrA) [Streptococcus salivarius strain KSS8]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSNQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKSGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=940682 V6U67_RS09970 WP_037611167.1 2126052..2127287(+) (htrA) [Streptococcus salivarius strain KSS8]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTGCTAGGTGGTTTGCTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAACCAAGACAAATCAAA
AGATTCTGATGGGTTGCAAGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGGAAAGAGGCCTACATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACG
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAGA
TTATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAATCTGGAGTGGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (7-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.635	98.783	0.569
htrA	Streptococcus pneumoniae Rx1	54.523	99.513	0.543
htrA	Streptococcus pneumoniae R6	54.523	99.513	0.543
htrA	Streptococcus pneumoniae TIGR4	54.523	99.513	0.543
htrA	Streptococcus pneumoniae D39	54.523	99.513	0.543
htrA	Streptococcus mitis NCTC 12261	54.523	99.513	0.543