Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   V6U67_RS01470 Genome accession   NZ_CP145865
Coordinates   275330..277426 (+) Length   698 a.a.
NCBI ID   WP_179968641.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS8     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 270330..282426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS01445 (V6U67_01450) trkA 270419..271768 (-) 1350 WP_014633874.1 Trk system potassium transporter TrkA -
  V6U67_RS01450 (V6U67_01455) - 272046..272555 (+) 510 WP_118172046.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  V6U67_RS01455 (V6U67_01460) - 272866..273423 (+) 558 WP_002883726.1 ECF transporter S component -
  V6U67_RS01460 (V6U67_01465) - 273426..274076 (+) 651 WP_002883719.1 phosphatase PAP2 family protein -
  V6U67_RS01465 (V6U67_01470) comR 274256..275155 (+) 900 WP_410531229.1 XRE family transcriptional regulator Regulator
  V6U67_RS01470 (V6U67_01475) comA 275330..277426 (+) 2097 WP_179968641.1 peptide cleavage/export ABC transporter Regulator
  V6U67_RS01475 (V6U67_01480) - 277536..277868 (+) 333 WP_014633880.1 DUF805 domain-containing protein -
  V6U67_RS01480 (V6U67_01485) - 277920..279314 (-) 1395 WP_272126731.1 DUF4153 domain-containing protein -
  V6U67_RS01485 (V6U67_01490) - 279702..280551 (+) 850 Protein_252 amino acid ABC transporter substrate-binding protein -
  V6U67_RS01490 (V6U67_01495) - 280711..281646 (+) 936 Protein_253 MetQ/NlpA family ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78525.47 Da        Isoelectric Point: 8.9687

>NTDB_id=940628 V6U67_RS01470 WP_179968641.1 275330..277426(+) (comA) [Streptococcus salivarius strain KSS8]
MSKYPYISQVDQRDCGVAALSMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQESLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLFAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGDVDEKELLKVCQHADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=940628 V6U67_RS01470 WP_179968641.1 275330..277426(+) (comA) [Streptococcus salivarius strain KSS8]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGTCCATGATTCTTAAACACTA
TGGTTCGTCTTATAGTTTGGCCTATTTGCGGGAGTTGGCTCAGACCTCTCGGGAAGGAACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCCATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAGCCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGACTGCAACATTATTATACGGTGTTTGGTCAAATCAAAGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGATTGATTGCAGTCATTGTCTTACTGAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTGACAATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGGAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCCTACCGATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACATCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCAATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCCCTTATTTTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTGCCTCTTTATGTTTTAATCATT
TTGGCCTTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAGAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACACAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTATGGTATGGGGCACAATTGGTCATGGAAGGACAGCTATTTGCAGGTCAGTTGATTACCTATAATAT
GTTACTGAATTATTTTACAACACCTTTAATTAATATTATCAATCTCCAATCCAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTCTT
AAGGGTGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACGACCTTAGCGAAAATGTTGTCAGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTAGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTCACAGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGATGTTGACGAGAAAGAGCTCCTTAAGGTTTGCCA
ACATGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACTCAAGTATCTGAGGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCCAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(494-640)

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter transmembrane region (ABC_membrane)

(167-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.69

98.997

0.532
  comA Streptococcus gordonii str. Challis substr. CH1

53.017

99.713

0.529
  comA Streptococcus mitis NCTC 12261

53.256

98.997

0.527
  comA Streptococcus pneumoniae Rx1

53.111

98.997

0.526
  comA Streptococcus pneumoniae D39

53.111

98.997

0.526
  comA Streptococcus pneumoniae R6

53.111

98.997

0.526
  comA Streptococcus pneumoniae TIGR4

52.967

98.997

0.524
  comA/nlmT Streptococcus mutans UA159

50

98.854

0.494