Detailed information NTG0940615

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: V6U66_RS10635
• Genome accession: NZ_CP145864
• Coordinates: 2242055..2243290 (+)
• Length: 411 a.a.
• NCBI ID: WP_013991347.1
• Uniprot ID: A0AB37CMH1
• Organism: Streptococcus salivarius strain KSS7
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2237055..2248290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS10615 (V6U66_10595)	-	2239378..2240397 (-)	1020	WP_171021848.1	IS30-like element IS1139 family transposase	-
V6U66_RS10625 (V6U66_10605)	-	2240671..2241354 (-)	684	WP_013991345.1	YoaK family protein	-
V6U66_RS10630 (V6U66_10610)	rlmH	2241370..2241849 (-)	480	WP_014632473.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
V6U66_RS10635 (V6U66_10615)	htrA	2242055..2243290 (+)	1236	WP_013991347.1	S1C family serine protease	Regulator
V6U66_RS10640 (V6U66_10620)	spo0J	2243356..2244123 (+)	768	WP_013991348.1	ParB/RepB/Spo0J family partition protein	Regulator
V6U66_RS10645 (V6U66_10625)	dnaA	2244362..2245726 (+)	1365	WP_013989871.1	chromosomal replication initiator protein DnaA	-

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42915.09 Da
• Isoelectric Point: 4.6266

>NTDB_id=940615 V6U66_RS10635 WP_013991347.1 2242055..2243290(+) (htrA) [Streptococcus salivarius strain KSS7]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=940615 V6U66_RS10635 WP_013991347.1 2242055..2243290(+) (htrA) [Streptococcus salivarius strain KSS7]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTGCTCGGTGGTTTGCTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCTGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAGCCAAGACAAATCAAA
AGATTCTGATGGGTTACAAGTCGCTGGTGAAGGTTCCGGTGTTATCTATAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATTCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAACAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAACCTTTACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (7-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus mitis NCTC 12261	54.279	99.513	0.54