Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   V6U66_RS05970 Genome accession   NZ_CP145864
Coordinates   1313944..1314651 (-) Length   235 a.a.
NCBI ID   WP_049529327.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1308944..1319651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS05945 (V6U66_05930) - 1309611..1310825 (+) 1215 WP_014633201.1 aminoacyltransferase -
  V6U66_RS05950 (V6U66_05935) - 1310927..1311203 (-) 277 Protein_1120 ISL3 family transposase -
  V6U66_RS05955 (V6U66_05940) - 1311375..1311734 (-) 360 WP_004182609.1 YbaN family protein -
  V6U66_RS05960 (V6U66_05945) vicX 1311793..1312605 (-) 813 WP_004182610.1 MBL fold metallo-hydrolase Regulator
  V6U66_RS05965 (V6U66_05950) vicK 1312611..1313951 (-) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U66_RS05970 (V6U66_05955) vicR 1313944..1314651 (-) 708 WP_049529327.1 response regulator YycF Regulator
  V6U66_RS05975 (V6U66_05960) - 1314940..1315707 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  V6U66_RS05980 (V6U66_05965) - 1315717..1316550 (+) 834 WP_049529326.1 transporter substrate-binding domain-containing protein -
  V6U66_RS05985 (V6U66_05970) - 1316568..1317266 (+) 699 WP_045772066.1 amino acid ABC transporter permease -
  V6U66_RS05990 (V6U66_05975) - 1317278..1317928 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6U66_RS05995 (V6U66_05980) - 1318115..1318882 (+) 768 WP_138261876.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27059.88 Da        Isoelectric Point: 4.7631

>NTDB_id=940585 V6U66_RS05970 WP_049529327.1 1313944..1314651(-) (vicR) [Streptococcus salivarius strain KSS7]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEVENPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=940585 V6U66_RS05970 WP_049529327.1 1313944..1314651(-) (vicR) [Streptococcus salivarius strain KSS7]
ATGAAAAAAATTCTAGTTGTTGATGACGAAAGACCAATTTCGGACATCATCAAGTTTAACCTGACTAAAGAGGGTTATGA
AGTGGTAACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGTTGAGAATCCTGACTTGGTAATCTTAGACTTAA
TGTTGCCTGAATTGGATGGCTTGGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.957

100

0.86
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387