Detailed information NTG0940556

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: V6U66_RS01435
• Genome accession: NZ_CP145864
• Coordinates: 265482..267578 (+)
• Length: 698 a.a.
• NCBI ID: WP_221739349.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS7
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 260482..272578

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS01405 (V6U66_01410)	-	260724..261233 (+)	510	WP_410534530.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
V6U66_RS01410 (V6U66_01415)	-	261544..262101 (+)	558	WP_037598980.1	ECF transporter S component	-
V6U66_RS01415 (V6U66_01420)	-	262104..262754 (+)	651	WP_048673883.1	phosphatase PAP2 family protein	-
V6U66_RS01420 (V6U66_01425)	-	262867..263253 (-)	387	WP_002886743.1	IS110 family transposase	-
V6U66_RS01425 (V6U66_01430)	-	263273..264034 (-)	762	WP_002886742.1	IS110 family transposase	-
V6U66_RS01430 (V6U66_01435)	comR	264408..265307 (+)	900	WP_049529071.1	helix-turn-helix transcriptional regulator	Regulator
V6U66_RS01435 (V6U66_01440)	comA	265482..267578 (+)	2097	WP_221739349.1	peptide cleavage/export ABC transporter	Regulator
V6U66_RS01440 (V6U66_01445)	-	267688..268020 (+)	333	WP_013990041.1	DUF805 domain-containing protein	-
V6U66_RS01445	-	268072..268491 (-)	420	WP_410534532.1	hypothetical protein	-
V6U66_RS01450 (V6U66_01455)	-	269048..269536 (+)	489	Protein_232	PDGLE domain-containing protein	-
V6U66_RS01455 (V6U66_01460)	-	269533..270312 (+)	780	WP_073687408.1	energy-coupling factor transporter transmembrane component T	-
V6U66_RS01460 (V6U66_01465)	-	270314..271030 (+)	717	WP_084871133.1	energy-coupling factor ABC transporter ATP-binding protein	-
V6U66_RS01465 (V6U66_01470)	-	271195..272043 (+)	849	WP_002883793.1	amino acid ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 78339.31 Da
• Isoelectric Point: 9.3518

>NTDB_id=940556 V6U66_RS01435 WP_221739349.1 265482..267578(+) (comA) [Streptococcus salivarius strain KSS7]
MSKYPYISQIDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIAHVVKEGGLQHYYTVFGQIKGQLIIGDPDPSKKVIKMPLEGFAKEWTGVALFFVPGKSYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIVQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKEFSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAIGHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMGGGQIESDSPNFNPFQFI

Nucleotide

• Length: 2097 bp

>NTDB_id=940556 V6U66_RS01435 WP_221739349.1 265482..267578(+) (comA) [Streptococcus salivarius strain KSS7]
ATGTCAAAATATCCATATATTTCACAGATTGATCAGCGTGATTGTGGTGTCGCTGCCTTAGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGACTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGCAGCTTAT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGGGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAAAATCCTATACTAAATACAAAGAAGATGTACCTGGGCTTCTTTCATTTTTACCGATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCTTACACTCTTCTGACCATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGAAATTACTTGTCCATTGCTGTCATC
CTTCCTTATATTAAGCATGTCCTTTCCTTACCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTGTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTGCCTCTTTATGTTTTAATCATT
TTGGCATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGAGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAAAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACTTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATTAATCTCCAATCCAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAAAAGGAAAACTTAAAGAGTTTTCTTTTAAACAACTTGCTCTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACAACCTTAGCGAAAATGTTGTCAGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTGGCCATGCGGAGTTACGTCAAATGGTGACTTATGTTCCCCAGCAGACCTATGTG
TTTACAGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTCCTTAAGGTATGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAGGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCCAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGCCGTGTAGTGACCATGGGGGGTGGTCAGATTGAGTCGGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter transmembrane region (ABC_membrane) (167-436)

• ABC transporter (ABC_tran) (494-640)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis SK321	53.69	98.997	0.532
comA	Streptococcus gordonii str. Challis substr. CH1	53.017	99.713	0.529
comA	Streptococcus mitis NCTC 12261	53.256	98.997	0.527
comA	Streptococcus pneumoniae Rx1	53.111	98.997	0.526
comA	Streptococcus pneumoniae D39	53.111	98.997	0.526
comA	Streptococcus pneumoniae R6	53.111	98.997	0.526
comA	Streptococcus pneumoniae TIGR4	52.967	98.997	0.524
comA/nlmT	Streptococcus mutans UA159	50.725	98.854	0.501