Detailed information NTG0940555

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: V6U66_RS01430
• Genome accession: NZ_CP145864
• Coordinates: 264408..265307 (+)
• Length: 299 a.a.
• NCBI ID: WP_049529071.1
• Uniprot ID: A0A6G4NCX0
• Organism: Streptococcus salivarius strain KSS7
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 259408..270307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS01405 (V6U66_01410)	-	260724..261233 (+)	510	WP_410534530.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
V6U66_RS01410 (V6U66_01415)	-	261544..262101 (+)	558	WP_037598980.1	ECF transporter S component	-
V6U66_RS01415 (V6U66_01420)	-	262104..262754 (+)	651	WP_048673883.1	phosphatase PAP2 family protein	-
V6U66_RS01420 (V6U66_01425)	-	262867..263253 (-)	387	WP_002886743.1	IS110 family transposase	-
V6U66_RS01425 (V6U66_01430)	-	263273..264034 (-)	762	WP_002886742.1	IS110 family transposase	-
V6U66_RS01430 (V6U66_01435)	comR	264408..265307 (+)	900	WP_049529071.1	helix-turn-helix transcriptional regulator	Regulator
V6U66_RS01435 (V6U66_01440)	comA	265482..267578 (+)	2097	WP_221739349.1	peptide cleavage/export ABC transporter	Regulator
V6U66_RS01440 (V6U66_01445)	-	267688..268020 (+)	333	WP_013990041.1	DUF805 domain-containing protein	-
V6U66_RS01445	-	268072..268491 (-)	420	WP_410534532.1	hypothetical protein	-
V6U66_RS01450 (V6U66_01455)	-	269048..269536 (+)	489	Protein_232	PDGLE domain-containing protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35174.66 Da
• Isoelectric Point: 5.8054

>NTDB_id=940555 V6U66_RS01430 WP_049529071.1 264408..265307(+) (comR) [Streptococcus salivarius strain KSS7]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKNMADLLDHDNITIPDEYYE
MKNRLIKFPTYRNPERIKDKLALIEEVYEKFFELLPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKKKFST
NDLLVIDYYFFHLYGRKQYDKKLFEKIVKRVLNQEIWTDDVHNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QFYSYKPSVFVLKAKYELLHKGNKKKATENYDKAIMFASVLEDSVLEESIKAGKAADGL

Nucleotide

• Length: 900 bp

>NTDB_id=940555 V6U66_RS01430 WP_049529071.1 264408..265307(+) (comR) [Streptococcus salivarius strain KSS7]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGTCAGCAGATGTCACGTGAAGTACTATGTTT
AGATGGTGCGGAGTTGACTGTTCGCCAGTTAATTCGCATTGAAAAAGGGGAATCTCTCCCGTCTTTAGATAGACTATCTT
ACATCGCAAAACGTCTAGGAAAAAATATGGCCGATCTATTGGATCATGACAATATTACTATCCCTGATGAATATTATGAG
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCAGAAAGAATAAAGGATAAACTTGCCTTAATTGAGGAAGT
CTATGAGAAATTCTTTGAACTTCTTCCAGAAGAAGAACTATTAACTCTAGATATTTTGGAAAATATATTAAGTTTCACTA
GTTGGGAGGAGAGTCCAAAGGTTGAGGAAATATATGAAGATTTATTTGAACAGGTCAAAAGGAAGAAGAAATTCTCAACT
AACGATTTATTAGTTATTGACTATTATTTCTTCCATCTTTATGGAAGAAAACAGTATGACAAAAAACTTTTTGAAAAAAT
CGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTCCATAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTGAAGATTTTTCACAATTCCTTTTCAGACTTCTTAACAGTTGTGGATAAAGCATTAGCCGTTATAGAAAAATCA
CAATTCTATAGCTATAAACCTAGTGTTTTTGTTCTCAAAGCTAAATATGAACTTCTGCATAAGGGAAATAAGAAAAAGGC
TACAGAGAATTACGATAAGGCCATAATGTTTGCTTCCGTTTTAGAAGACTCGGTTTTAGAAGAAAGTATAAAAGCAGGGA
AAGCGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (75-292)

3D structure

• AlphaFold DB: A0A6G4NCX0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus salivarius strain HSISS4	96.99	100	0.97
comR	Streptococcus salivarius SK126	96.321	100	0.963
comR	Streptococcus thermophilus LMG 18311	93.98	100	0.94
comR	Streptococcus thermophilus LMD-9	93.311	100	0.933
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421