Detailed information NTG0940544

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: V6U65_RS10175
• Genome accession: NZ_CP145863
• Coordinates: 2173773..2175008 (+)
• Length: 411 a.a.
• NCBI ID: WP_070439652.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS6
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2168773..2180008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U65_RS10145 (V6U65_10140)	-	2169245..2171839 (+)	2595	WP_410532473.1	YfhO family protein	-
V6U65_RS10165 (V6U65_10160)	-	2172389..2173072 (-)	684	WP_002883977.1	YoaK family protein	-
V6U65_RS10170 (V6U65_10165)	rlmH	2173088..2173567 (-)	480	WP_014632473.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
V6U65_RS10175 (V6U65_10170)	htrA	2173773..2175008 (+)	1236	WP_070439652.1	S1C family serine protease	Regulator
V6U65_RS10180 (V6U65_10175)	spo0J	2175074..2175841 (+)	768	WP_014635206.1	ParB/RepB/Spo0J family partition protein	Regulator
V6U65_RS10185 (V6U65_10180)	dnaA	2176080..2177444 (+)	1365	WP_049553505.1	chromosomal replication initiator protein DnaA	-

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42888.06 Da
• Isoelectric Point: 4.6266

>NTDB_id=940544 V6U65_RS10175 WP_070439652.1 2173773..2175008(+) (htrA) [Streptococcus salivarius strain KSS6]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYSNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=940544 V6U65_RS10175 WP_070439652.1 2173773..2175008(+) (htrA) [Streptococcus salivarius strain KSS6]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTACTAGGTGGTTTACTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACCGATACAGGTGTTAAAACAGCTAAGACCGTATACA
GTAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGATTCTAGCCAAGACAAATCAAA
AGATTCTGATGGGTTGCAAGTCGCTGGTGAAGGTTCCGGTGTCATCTATAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCAGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATATGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGTCAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

• Peptidase family M50 (Peptidase_M50) (7-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus mitis NCTC 12261	54.279	99.513	0.54