Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   V6U65_RS04435 Genome accession   NZ_CP145863
Coordinates   904661..905368 (+) Length   235 a.a.
NCBI ID   WP_037600497.1    Uniprot ID   A0AAW7PG55
Organism   Streptococcus salivarius strain KSS6     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 899661..910368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U65_RS04410 (V6U65_04410) - 900422..901189 (-) 768 WP_070476864.1 amino acid ABC transporter ATP-binding protein -
  V6U65_RS04415 (V6U65_04415) - 901378..902028 (-) 651 WP_183137164.1 amino acid ABC transporter permease -
  V6U65_RS04420 (V6U65_04420) - 902040..902738 (-) 699 WP_410532946.1 amino acid ABC transporter permease -
  V6U65_RS04425 (V6U65_04425) - 902756..903589 (-) 834 WP_175061770.1 transporter substrate-binding domain-containing protein -
  V6U65_RS04430 (V6U65_04430) - 903599..904366 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  V6U65_RS04435 (V6U65_04435) vicR 904661..905368 (+) 708 WP_037600497.1 response regulator YycF Regulator
  V6U65_RS04440 (V6U65_04440) vicK 905361..906701 (+) 1341 WP_013990681.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U65_RS04445 (V6U65_04445) vicX 906707..907519 (+) 813 WP_048790820.1 MBL fold metallo-hydrolase Regulator
  V6U65_RS04450 (V6U65_04450) - 907578..907937 (+) 360 WP_045769141.1 YbaN family protein -
  V6U65_RS04455 (V6U65_04455) - 907989..909203 (-) 1215 WP_048790819.1 aminoacyltransferase -
  V6U65_RS04460 (V6U65_04460) yidA 909205..910014 (-) 810 WP_002890845.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27072.92 Da        Isoelectric Point: 4.8387

>NTDB_id=940508 V6U65_RS04435 WP_037600497.1 904661..905368(+) (vicR) [Streptococcus salivarius strain KSS6]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTNHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=940508 V6U65_RS04435 WP_037600497.1 904661..905368(+) (vicR) [Streptococcus salivarius strain KSS6]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCGATTTCGGATATCATCAAGTTTAATCTAACTAAAGAGGGTTATGA
AGTTGTTACGGCCTTTGATGGTCGTGAAGCATTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGCTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAATCATACACCAATTATCATGCTTTCAGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCAGATGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCAGGCA
AGCAGGAAATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.106

100

0.851
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.136

100

0.383