Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V6U65_RS04440 Genome accession   NZ_CP145863
Coordinates   905361..906701 (+) Length   446 a.a.
NCBI ID   WP_013990681.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS6     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 900361..911701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U65_RS04410 (V6U65_04410) - 900422..901189 (-) 768 WP_070476864.1 amino acid ABC transporter ATP-binding protein -
  V6U65_RS04415 (V6U65_04415) - 901378..902028 (-) 651 WP_183137164.1 amino acid ABC transporter permease -
  V6U65_RS04420 (V6U65_04420) - 902040..902738 (-) 699 WP_410532946.1 amino acid ABC transporter permease -
  V6U65_RS04425 (V6U65_04425) - 902756..903589 (-) 834 WP_175061770.1 transporter substrate-binding domain-containing protein -
  V6U65_RS04430 (V6U65_04430) - 903599..904366 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  V6U65_RS04435 (V6U65_04435) vicR 904661..905368 (+) 708 WP_037600497.1 response regulator YycF Regulator
  V6U65_RS04440 (V6U65_04440) vicK 905361..906701 (+) 1341 WP_013990681.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U65_RS04445 (V6U65_04445) vicX 906707..907519 (+) 813 WP_048790820.1 MBL fold metallo-hydrolase Regulator
  V6U65_RS04450 (V6U65_04450) - 907578..907937 (+) 360 WP_045769141.1 YbaN family protein -
  V6U65_RS04455 (V6U65_04455) - 907989..909203 (-) 1215 WP_048790819.1 aminoacyltransferase -
  V6U65_RS04460 (V6U65_04460) yidA 909205..910014 (-) 810 WP_002890845.1 sugar-phosphatase -
  V6U65_RS04465 (V6U65_04465) - 910192..911058 (+) 867 WP_410532950.1 GNAT family N-acetyltransferase -
  V6U65_RS04470 (V6U65_04470) - 911141..911527 (+) 387 WP_048790817.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50929.21 Da        Isoelectric Point: 5.1606

>NTDB_id=940509 V6U65_RS04440 WP_013990681.1 905361..906701(+) (vicK) [Streptococcus salivarius strain KSS6]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=940509 V6U65_RS04440 WP_013990681.1 905361..906701(+) (vicK) [Streptococcus salivarius strain KSS6]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGAGTCAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
CTCAGATGTCCATTTTAGATTTATTAGATGGTGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTATCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAACTTTGCCCTAATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCATGATGCTACTGAGCAGGAAAAAGAAGAGCGTGAACGTCGACTTTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGAGCTCTCGATGAA
GAGATTGCACCTAACTTCATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAGAGTCAAGAAACCAATACAGGTAAAACTTACGAAATTATTCGAGATTATCCGGTAAACTCAATT
TGGGTAGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCCATTAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCAAGAAGTCGTGCCCAGGGTGGAACTGGTCTT
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAAGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657