Detailed information NTG0940468

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: V6U64_RS08765
• Genome accession: NZ_CP145862
• Coordinates: 1905113..1907209 (-)
• Length: 698 a.a.
• NCBI ID: WP_175057392.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS4
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1900113..1912209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U64_RS08735 (V6U64_08735)	-	1901656..1901967 (-)	312	WP_002886559.1	urease subunit beta	-
V6U64_RS08740 (V6U64_08740)	-	1901979..1902281 (-)	303	WP_002886558.1	urease subunit gamma	-
V6U64_RS08745 (V6U64_08745)	-	1902306..1902821 (-)	516	WP_002886548.1	AmiS/UreI family transporter	-
V6U64_RS08750 (V6U64_08750)	-	1903228..1903911 (+)	684	WP_260313887.1	urease cluster protein	-
V6U64_RS08755 (V6U64_08755)	-	1903978..1904619 (+)	642	WP_230310562.1	DUF4153 domain-containing protein	-
V6U64_RS08760 (V6U64_08760)	-	1904670..1905002 (-)	333	WP_002886546.1	DUF805 domain-containing protein	-
V6U64_RS08765 (V6U64_08765)	comA	1905113..1907209 (-)	2097	WP_175057392.1	peptide cleavage/export ABC transporter	Regulator
V6U64_RS08770 (V6U64_08770)	comR	1907384..1908283 (-)	900	WP_073685698.1	helix-turn-helix transcriptional regulator	Regulator
V6U64_RS08775 (V6U64_08775)	-	1908462..1909112 (-)	651	WP_022496033.1	phosphatase PAP2 family protein	-
V6U64_RS08780 (V6U64_08780)	-	1909115..1909672 (-)	558	WP_022496034.1	ECF transporter S component	-
V6U64_RS08785 (V6U64_08785)	-	1909962..1910471 (-)	510	WP_002883735.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
V6U64_RS08790 (V6U64_08790)	trkA	1910763..1912112 (+)	1350	WP_022496357.1	Trk system potassium transporter TrkA	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 78642.59 Da
• Isoelectric Point: 9.2818

>NTDB_id=940468 V6U64_RS08765 WP_175057392.1 1905113..1907209(-) (comA) [Streptococcus salivarius strain KSS4]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIVHVVKEGGLQHYYTVFGQIKGQLVIGDPDPSKKVIKMPLEEFAKEWTGVTLFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQAIIDRLIPQGAYNLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIVQNQSLFVMTLTVVPLYVLII
VVFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEDRRYREIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMERQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAF
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGQSGSGKTTLAKMLSGYYTKSSGHVTLDKDTISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLIKVCQQADILEDIQRMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSANFNPFQFI

Nucleotide

• Length: 2097 bp

>NTDB_id=940468 V6U64_RS08765 WP_175057392.1 1905113..1907209(-) (comA) [Streptococcus salivarius strain KSS4]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCTATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGAGAGTTGGCTCAGACTTCTCGTGAAGGTACTTCTGCGCTTGGTTTGGTGG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGTACATGTGGTTAAAGAAGGTGGGCTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGCAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAATTTGCCAAAGAGTGGACGGGAGTTACTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTACCTGGACTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTATTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAAGCTATTATCGACCGTTTGATTCCTCAGGGGGCCTATAATCTTCTGACCATGATTTCGCTAGGCTTATGCATCTCTT
ATCTTGCTCAACAAGTTTTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGTAATTACCTGTCCATTGCTGTCATT
CTTCCTTATATCAAGCATGTCCTTTCCTTGCCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGAGATGCTAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTGTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTTCCTCTTTATGTTTTAATCATT
GTGGTATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGTATTGAAACCTTAAAATCCTTGAGAGTTGAGGATAGACGTTATCGGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCCTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGGTTAAAGACAGGGGTTCAGTTAGTTTCT
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTTATGGAAAGGCAACTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGTTGAATTATTTTACAACTCCTTTAATTAATATCATCAATCTCCAATCTAAAATTCAGCAAGCCAAAGTCGCCAATA
ATCGTCTTCAAGAAGTATATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTTTT
AAAGGAGTTAGTCACCGTTTTAGTTATCAGCAAGAGACTCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTCAGAGTGGTTCTGGAAAAACGACCTTAGCTAAAATGTTGTCAGGTTATTATACGAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATACCATTAGCCATGCGGAGTTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACGGGGACGATTTTAGAGAATCTTCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTTATTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAGAATGCCACTAGGCTTTCAGACCCAAGTATCTGAAGACGGTGGTTTGTCTG
GCGGTCAAAAACAAAGATTAGCTATAGCAAGGGCTCTATTGTCCAAACAACCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTACGTCAACATGTCAGTCGTGTAGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTGCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-139)

• ABC transporter (ABC_tran) (494-640)

• ABC transporter transmembrane region (ABC_membrane) (167-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis SK321	53.546	98.997	0.53
comA	Streptococcus gordonii str. Challis substr. CH1	53.017	99.713	0.529
comA	Streptococcus mitis NCTC 12261	53.111	98.997	0.526
comA	Streptococcus pneumoniae Rx1	52.967	98.997	0.524
comA	Streptococcus pneumoniae D39	52.967	98.997	0.524
comA	Streptococcus pneumoniae R6	52.967	98.997	0.524
comA	Streptococcus pneumoniae TIGR4	52.822	98.997	0.523
comA/nlmT	Streptococcus mutans UA159	50.435	98.854	0.499